Protein Alignment Nep1 and nep-24

DIOPT Version :9

• Sequence 1: NP_001284925.1
• Gene: Nep1 / 31547
• FlyBaseID: FBgn0029843
• Length: 849
• Species: Drosophila melanogaster
• Sequence 2: NP_503005.3
• Gene: nep-24 / 190993
• WormBaseID: WBGene00013786
• Length: 567
• Species: Caenorhabditis elegans
• Alignment Length: 616
• Identity: 127/616 - (20%)
• Similarity: 242/616 - (39%)
• Gaps: 139/616 - (22%)

  Fly   163 GSAHEGQDNICMTQECVRTAASLLSAMDLNSDPCEDFFQYACGTWNKMHPIPEDRSSISTFEVLS 227
            |:......|:|.|..|:..|..|.:..|.:.|||::|.|:|||..::..  .||..:..|..:.:
 Worm    28 GATTPATRNVCNTPACITLAHMLHNYHDPSVDPCDNFHQFACGREHEHE--TEDIYTKKTKTINN 90

  Fly   228 DQQQVILRAVLEEPIDERDNKATIKAKTFFKSCMDIPQ----IRKIGTGRLKQVLQSLGGWPVIE 288
                 |::..|::....| :|:....:|.:|:|..:.:    .|......:.|.:||:|.|||::
 Worm    91 -----IMKRFLKKNETSR-SKSENAMRTLYKACKTLEKNSTASRNKALQDIFQDIQSIGAWPVVD 149

  Fly   289 RNWSPPA-DLSVERLMGQLRLNYSEPVMIELYVGADDKNSSV-----------------NILQMD 335
            ..|.... ||: :.|:..:||......:.::....:.:|.::                 .||:.:
 Worm   150 DKWDESKFDLN-DFLVNLVRLGRKNFGLFQMARYVNVRNFAIGPEAAWRHNVDLGKTISEILKAN 213

  Fly   336 QLQYALPSRDYYLKESSANDRRAYHRYMTQVALLLGADPATAAAELEKVV---LFETQLVNVSLP 397
            .:|              .|:::           ||  |.......|||.:   .|.|........
 Worm   214 SVQ--------------TNNKK-----------LL--DDLAEYVNLEKALSQHKFNTVQPGYIFS 251

  Fly   398 EADRHDTSLVYRKMLL----PELQELVPEVQWQEYLQAALGPGIPLQEDEPLVTYGLHYLTE--- 455
            |.....:|:.:.:::|    |:.:.|.|||                        |.:.|||.
 Worm   252 ERSDFVSSVNFSRLVLEMMSPDKRTLFPEV------------------------YQIMYLTNTSL 292

  Fly   456 -MGK------ILAHTDRRVVHNYMLWRLVMSLMSHMIDEYQRERVEFRKILMGIQSERTRWSQCV 513
             .||      |:.:|.:|.:.||::::.:.:.::              .:..|..|     :.|.
 Worm   293 FFGKNNNLETIIRNTSKRALANYLIFKFIDTSIA--------------DLTYGSPS-----AFCE 338

  Fly   514 EWTNKKLGVAVGALFIRDNFNQESKEVALEMIHTIRAAFNELLAENDWMDDETRAVAKEKADSMN 578
            :.....|..|....|.|:..::|:::...::....:....:::...|||..:::.:|.::..|||
 Worm   339 QKVINFLPRAALRAFYRNFISKENRKKITKLTEATQVQLLKIIGATDWMSIKSKKIAMDRVSSMN 403

  Fly   579 ERIGYPELLTNATELEQ--EYVNLTIVPDNFINNVLSILQWESEKMLRLLRQPVDKEKWTTE--- 638
            ..||||:......:|:.  |::||: ..|.:...|        .|:.|.:|:. :.:.:|.|
 Worm   404 MVIGYPDYFDPPGKLDGLFEHLNLS-SSDTYYTVV--------RKINRFMREQ-EMDYYTGEVPY 458

  Fly   639 ----PAVV-NAFYNPNKNDIVFPAGILQPLFYSQHFPKSLNYGGIGVVIGHEITHGFDDKGRQFD 698
                |.:: ||.||.|.|:::..|......|:...||...|.......:.||:.|.|.......
 Worm   459 YPLFPGLMTNAMYNANDNNLMIFAPFFDDPFFDSSFPDYANIAFTSNTLAHEMGHTFSPHLMDI- 522

  Fly   699 KEGNMMQWWNNATIEAFRERTQCVIDQYSRY 729
            ..|....|......|.:.:|.:|:.|||:.|
 Worm   523 MTGTTEVWLTPKETEEYEKRVKCLEDQYTEY 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep1	NP_001284925.1	M13	194..847	CDD:189000	119/585 (20%)
nep-24	NP_503005.3	GluZincin	58..561	CDD:301352	119/586 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920