Protein Alignment Nep1 and nep-20

DIOPT Version :9

• Sequence 1: NP_001284925.1
• Gene: Nep1 / 31547
• FlyBaseID: FBgn0029843
• Length: 849
• Species: Drosophila melanogaster
• Sequence 2: NP_001317749.1
• Gene: nep-20 / 188176
• WormBaseID: WBGene00020293
• Length: 834
• Species: Caenorhabditis elegans
• Alignment Length: 755
• Identity: 155/755 - (20%)
• Similarity: 282/755 - (37%)
• Gaps: 197/755 - (26%)

  Fly   163 GSAHEGQDNICMTQECVRTAASLLSAMDLNSDPCEDFFQYACGTWNKMHPIPEDRSSISTFEVLS 227
            |:..:.:.::|.:.:|:..|..|.:..|.:...|.:|::..||.:.....:.:.|.        :
 Worm   205 GARQDEKPSLCESPQCITLAFELSAYQDTSVSKCHNFYKATCGKYKHHQALDKHRD--------A 261

  Fly   228 DQQQVILRAVLEEPIDERDNKATIKAK------TFFKSCMDIPQIRKIGTGRLKQVLQSLGGWPV 286
            .:::|:.|.|.|   ..|.|:::|.:|      ..|..|....| .|......|.: :.:|.|||
 Worm   262 KKKEVVKRIVRE---FLRRNESSITSKFEPAIRLMFGKCNKFSQ-NKTYLDIFKDI-EKIGPWPV 321

  Fly   287 IERNWSPPADLSVERLMGQLRLNYSEPVMIELYVGADDKNSSVNILQMDQLQYALPSRDYYLK-- 349
            ::.:|                    ..||..|                         .||.|.
 Worm   322 LKSDW--------------------VDVMFNL-------------------------NDYLLSLV 341

  Fly   350 ESSANDRRAYHRYMTQVALLLGADPATAAAE------LEKVVLFETQLVNVSLPEADRHDTSLVY 408
            |....|...:.....|:|  .|..|..|.:|      |||::|   :::..:..:|||...|...
 Worm   342 ELGFTDFGLFKLEFRQLA--FGQFPVIAPSEQKQGNQLEKIIL---EILEANGVQADRQKLSKYL 401

  Fly   409 RKM--LLPELQELVPE---VQWQEYLQAALGPGIP--LQEDEPLVT-YGLHYLTEMG-------- 457
            |:.  ...:|:.:..|   |::..|..:.|...|.  :|:..|:.| .||....:.|
 Worm   402 REYSEFKSQLRHMSLEGTSVKYIRYNASTLSVNISALVQKMAPMSTSSGLVRRIQSGILITNSSS 466

  Fly   458 -------KILAHTDRRVVHNYMLWRLVMSLMSHMIDEYQRERVEFRKILMGIQSERTRWSQCVEW 515
                   .|:..|.:|.:.||:::        |.||              .:..:.|..::..|.
 Worm   467 FFGKNLDAIIQQTHKRTLANYLIF--------HFID--------------AVTFDLTSGAKHSEH 509

  Fly   516 TNKKLGVAVGALFI--RDNFNQESKEVALEMIHTIRAAFNELLAENDWMD-------DETRAVAK 571
            |...| :..|:|.:  :|..::|.:.|.:||...::....|:::|...:|       ::.|....
 Worm   510 TLIDL-LPRGSLQVLSQDFVDEEDQGVMVEMAKDLKKHVVEMISEGSSLDKGHLVFEEKERRKLI 573

  Fly   572 EKADSMNERIGYPELLTNATELEQEYVNLTIVPDNFINNVLSIL-QWESEKMLRLL---RQPVDK 632
            .|...:.....||..:.|     |.:..|.:...:.::.::..| ::.||:::..|   ..|.||
 Worm   574 RKVQDILVVTKYPLEILN-----QNFEKLNLTYSDSLHKIIQKLRRFRSEQLIEYLGGDLDPTDK 633

  Fly   633 EKWTTEPAVVNAFYNPNKNDIVFPAGILQPLFYSQHFPKSLNYGGIGVVIGHEITHGFDDKGRQF 697
            ..|.      :|.|....||::..|.|:...::...:|..:|...:|.:|..|:....|....:.
 Worm   634 GMWG------SAHYEQATNDLIIIAPIIDGPYFDTSYPNYVNIFFMGFIISRELGRSLDSVRIRK 692

  Fly   698 DKEGNMMQWWNNATIEAFRERTQCVIDQYSRYKINEVDMFMDGRMTQGENIADNGGLKQAFRAYK 762
            |::|:...|..:.:::.|....:|     .|.||.       |.....|.:||:.|.:.:|.|.|
 Worm   693 DEKGHTENWLKSESLKRFDNNVKC-----WRKKIT-------GTRFLNEMLADHVGHEASFMALK 745

  Fly   763 KW---------ETLHGREQQLPGLNMTHDQLFFLNYAQIWC-------GSMRPEDA----LTKIR 807
            ||         |.:.|.|      :||.:|:||...|..:|       |.:..:||    .|::.
 Worm   746 KWEKEMNGTIVEKIRGYE------SMTMEQIFFHLQALYFCRPPGGSTGELTAKDARQHYSTRVN 804

  Fly   808 SAVHSPGFVRVLGPLSNSRDFASAYKCPLGSTMNPAEKCS 847
            .|            ..|...||.|:.|.....||...||:
 Worm   805 EA------------FKNMPQFAKAFGCSSNQNMNSKTKCT 832

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep1	NP_001284925.1	M13	194..847	CDD:189000	148/722 (20%)
nep-20	NP_001317749.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920