Protein Alignment Nep1 and nep-8

DIOPT Version :9

• Sequence 1: NP_001284925.1
• Gene: Nep1 / 31547
• FlyBaseID: FBgn0029843
• Length: 849
• Species: Drosophila melanogaster
• Sequence 2: NP_001309548.1
• Gene: nep-8 / 184631
• WormBaseID: WBGene00017553
• Length: 686
• Species: Caenorhabditis elegans
• Alignment Length: 723
• Identity: 150/723 - (20%)
• Similarity: 300/723 - (41%)
• Gaps: 128/723 - (17%)

  Fly   114 LVLAIAFTVLGAAIGALAIYFASVHQRCHLYRLEPDNDDRPNGRWNQ-DSGSAHEGQDNICMTQE 177
            |:|.|.|..:           .:||     .::||.|.|......|. ||       .|:|.:.|
 Worm    19 LLLLIVFLAM-----------VTVH-----IKVEPVNLDELLSIGNDVDS-------KNLCDSPE 60

  Fly   178 CVRTAASLLSAMDLNSDPCEDFFQYACGTWNKMHPIPEDRSSISTFEVLSDQQQVILRAVLEEPI 242
            |:..:..||:..|.:.|||.||||::||.:::.          |..|....:::.|||..:.|.:
 Worm    61 CITLSHELLNYQDPSVDPCVDFFQHSCGRFHEQ----------SVSESRLQKKKHILRKQIREFL 115

  Fly   243 DERDNKATIKAKTFFKSCMDIPQIR--------KIGTGRLKQV---LQSLGGWPVIERNW-SPPA 295
            .:..| :|.|::...|...|..:..        ||....:..|   ::.:|.||::::|| ....
 Worm   116 HKIQN-STSKSENLMKLVFDKCEASKKTSNDNYKISRDAIHDVFNDIKKIGAWPLLDKNWDGSKF 179

  Fly   296 DLSVERLMGQLRLNYSEPVMIELYVGADDKNSSVNILQMDQLQYALPSRDYYLKESSANDRRAYH 360
            ||: |.|...::|            ||.:       |.:.||.:.:.:...:::.:.......::
 Worm   180 DLN-EMLSNLVKL------------GATN-------LGLFQLDFRILTEGKFVRIAPTLGSIVHN 224

  Fly   361 RYM-TQVALLLGA-----DPATAAAELEKVVLFETQL--------VNVSLPEADRHDTSLVYRKM 411
            ..| :.::.:|.|     |....:.|.|:....:.:|        :::|||.....:.|.:..:|
 Worm   225 STMISMISEILEANGVQPDSEEISKEFEEYSSLQMKLAKYQSSGKLSISLPGVRSINFSSLITEM 289

  Fly   412 LLP-ELQELVPEVQWQEYLQAALGPGIPLQEDEPLVTYGLHYLTEMGKILAHTDRRVVHNYMLWR 475
            :.| .:.::..:::             .:..:.||. :..:....:..|:..|..:.:.|::::.
 Worm   290 IHPSRVSKIFGKIR-------------VVTSEHPLF-FKSNETESLDTIIESTSNKTLANFLIFN 340

  Fly   476 LVMSLMSHMIDEYQRERVEFRKILMGIQSERTRWSQCVEWTNKKLGVAVGALFIRDNFNQESKEV 540
            .:.|..:               |:.|     .|...|.:...::...|...:|:|:..::.:::.
 Worm   341 YIQSSYN---------------IMKG-----ARRGNCEDDVRREFPRASLRVFMRNFVDKGNRDG 385

  Fly   541 ALEMIHTIRAAFNELLAENDWMDDETRAVAKEKADSMNERIGYPELLTNATELEQEYVNLTI-VP 604
            ..::...::....|::.:.:.:....:....:|.:::...||||:.......|::|:.|..: ..
 Worm   386 VKKLTEELKKNTLEMIQDTENLAPPVKESMLKKVEAIKVTIGYPDHFDPPGTLDKEFENFDLDST 450

  Fly   605 DNFINNVLSILQWESEKMLRLL--RQPVDKEKWTTEPAVVNAFYNPNKNDIVFPAGILQPLFYSQ 667
            |::......:.:..||:.:..:  ..|:...|   |...|||.|..:||.:...|..|...|:..
 Worm   451 DSYYRIFQKLNRLRSEQQMEFIAGETPISPIK---EVLKVNANYKRSKNALTVFAPFLDDPFFDI 512

  Fly   668 HFPKSLNYGGIGVVIGHEITHGFDDKGRQFDKEGNMMQWWNNATIEAFRERTQCVIDQYSRYKIN 732
            .:|..:|....|.:|.|||.|..|..|..:|:.|..|.......:..:.::.||::|||..|...
 Worm   513 TYPDYVNLFFSGFLIAHEIGHSVDANGLGYDENGKPMDGIRLEHVTEYGKQGQCLVDQYDNYDDP 577

  Fly   733 EVDMFMDGRMTQGENIADNGGLKQAFRAYKKWETLHGREQQLPGL-NMTHDQLFFLNYAQIWCGS 796
            .....|:|..:..|.|||..|.:..:|||||.:|  .:...|.|| ::..|||:|...:.::|
 Worm   578 VYGKKMNGTHSINEIIADWVGHEVTWRAYKKMDT--SKMLSLIGLKDINMDQLYFRVQSLLFC-- 638

  Fly   797 MRPEDALT 804
             |..|.::
 Worm   639 -RERDTIS 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep1	NP_001284925.1	M13	194..847	CDD:189000	130/642 (20%)
nep-8	NP_001309548.1	M13	76..664	CDD:341056	130/643 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920