Protein Alignment Nep1 and nep-23

DIOPT Version :10

• Sequence 1: NP_511056.2
• Gene: Nep1 / 31547
• FlyBaseID: FBgn0029843
• Length: 849
• Species: Drosophila melanogaster
• Sequence 2: NP_503004.2
• Gene: nep-23 / 178472
• WormBaseID: WBGene00013785
• Length: 714
• Species: Caenorhabditis elegans
• Alignment Length: 824
• Identity: 177/824 - (21%)
• Similarity: 318/824 - (38%)
• Gaps: 213/824 - (25%)

  Fly   113 LLVLAIAFTVLGAAI----------------------GALAIYFASV--HQRCHLYRLEPDNDDR 153
            :|:|.:...:.|..:                      |.|.:...|:  |:..||
 Worm    17 ILLLIVVIAIFGTVVIWKIDKLELWEAEALSSQESMLGELKVAVTSLEQHRPGHL---------- 71

  Fly   154 PNGRWNQDSGSAHEGQDNICMTQECVRTAASLLSAMDLNSDPCEDFFQYACGTWNKMHPIPEDRS 218
                           :.|:|.|.||:..|..|.:..|.::|||::|:|..||..:: |.:   :|
 Worm    72 ---------------KKNVCQTPECITLAHQLHNYHDPSADPCDNFYQSVCGKQHE-HSL---KS 117

  Fly   219 SISTFEVLSDQQQVILRAVLEEPIDERDNKATIKAKTFFK-------------SCMDIPQ--IRK 268
            .::       ::.:|||.::.|.|..|....|.|::...:             |..||.|  :|.
 Worm   118 GLA-------KKHLILRNLIRETITNRKVTPTSKSENEMRKFHGICSKYQRANSSSDIAQQALRD 175

  Fly   269 IGTGRLKQVLQSLGGWPVIERNWSPPADLSVERLMGQLRLNYSEPVMIELYVGADDKNSSVNILQ 333
            |    .:.| ||:|.||...|||: .:|.::..::.                         |:::
 Worm   176 I----FRDV-QSIGSWPAGSRNWN-ESDFNLNEMLN-------------------------NLVK 209

  Fly   334 MDQLQYALPSRDYYLKE----SSANDRRAYHRYMTQVALL-----LGADPATAAAELEKVVLFET 389
            :.|..:.|....:..::    |:...||.|.:....:..:     |..|......:||.....|.
 Worm   210 LGQRNFGLFQISFKYRDQLLISAEEHRRNYSKLEPTILNIFETNGLVPDRIQLLKDLEGFASLEA 274

  Fly   390 QLVN-VSLPEADRHDTSLVYRKMLLPELQELVPEVQWQEYLQAALGPG----IP----------- 438
            .|.| ..|...|         ||....|.:|||.|.:...::|.:.||    :|
 Worm   275 LLKNHYYLDNMD---------KMKPAVLDDLVPSVDFMGLVKAMISPGKEHLMPKIELKTSVLNQ 330

  Fly   439 -LQEDEPLVTYGLHYLTEMGKILAHTDRRVVHNYMLWRLVMSLMSHMIDEYQRERVEFRKILMGI 502
             |..||.:         .:..|:..|.:|.:.||:::..:.|.:.|::                .
 Worm   331 TLFNDENM---------NLEAIILDTPKRTLANYLIFNFIDSSLDHLV----------------F 370

  Fly   503 QSERTRWSQCVEWTNKKLGVAVGALFIRDNFNQESKEVALEMIHTIRAAFNELLAENDWMDDETR 567
            ::...:.:.|.:.....|..|...:|||:..::|::::..::....|.|.:.|:..:.|:..|::
 Worm   371 ETTSQKGNTCEDKVITYLPRASLRVFIRNYVDKENRDLITQLAEKTRIALHTLVQNSTWLKAESK 435

  Fly   568 AVAKEKADSMNERIGYPELLTNATELEQEYVNLTIVPDNFINNVLSILQ--WESEKMLRLLRQ-P 629
            .:|.:|.::|.:.||||:.......|:..:.||.:...:.....|:.|:  :..:||.....: |
 Worm   436 QLALDKINAMGKMIGYPDFFEPPGTLDGMFKNLNLDSSDTYYTALNKLERYFVEQKMDYFAEETP 500

  Fly   630 VDKEKWTTEPAVVNAFYNPNKNDIVFPAGILQPLFYSQHFPKSLNYGGIGVVIGHEITHGFDD-- 692
            :|.:....|   :||:|....|.:.|.|.......:...:|..:|....|.:||||:.|.|..
 Worm   501 LDPDLRVFE---MNAYYYIPGNQLNFLAPFFDDPMFDSTYPDYVNIAMSGNIIGHEMGHAFGPHA 562

  Fly   693 -----KGRQFDKEGNMMQWWNNATIEAFRERTQCVIDQYSRYKINEVDMFMDGRMTQGENIADNG 752
                 :||:.        |.....:..:..|.||:.:|||.|...:.....||.....|.:|||.
 Worm   563 ILRTVRGREV--------WMKPEELAEYESRAQCLANQYSEYDDPDFGRVFDGGKVIDELVADNI 619

  Fly   753 GLKQAFRAYKKWETLHGREQQLPGLNMTH------------DQLFFLNYAQIWCGSMRPEDALTK 805
            |.:.:::.:|             .|::|:            |||:|...|...|......|....
 Worm   620 GREVSWKMFK-------------SLDLTNATRIIGFEDYDIDQLYFRVGALTHCTPHAMRDLKGS 671

  Fly   806 IRSAVHSPGFVRVLGPLSNSRDFASAYKCPLGSTMNPAEKCSVW 849
            |.|: |.....||.|..:|..:||.|:.||.||.|||.:||.::
 Worm   672 IESS-HPRKAFRVNGVYANLPEFARAFNCPTGSPMNPRKKCDMF 714

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep1	NP_511056.2	M13	194..847	CDD:341056	159/715 (22%)
nep-23	NP_503004.2	M13	96..711	CDD:341056	158/715 (22%)