Protein Alignment Nep1 and nep-1

DIOPT Version :9

• Sequence 1: NP_001284925.1
• Gene: Nep1 / 31547
• FlyBaseID: FBgn0029843
• Length: 849
• Species: Drosophila melanogaster
• Sequence 2: NP_496490.2
• Gene: nep-1 / 174787
• WormBaseID: WBGene00013926
• Length: 754
• Species: Caenorhabditis elegans
• Alignment Length: 690
• Identity: 252/690 - (36%)
• Similarity: 390/690 - (56%)
• Gaps: 21/690 - (3%)

  Fly   176 QECVRTAASLLSAMDLNSDPCEDFFQYACGTWNKMHPIPEDRSSISTFEVLSDQQQVILRAVLEE 240
            ||..|.   |..:::|:.|||:|||:|||..|...||||:|.:|.|.|....::....:|.:.|:
 Worm    70 QEASRL---LQKSLNLSLDPCDDFFEYACRAWVDSHPIPDDLTSYSQFTATREKVLAEMRKLYED 131

  Fly   241 PIDERDNKATIKAKTFFKSCMDIPQIRKIGTGRLKQVLQSLGGWPVIERNWSPPADLSVERLMGQ 305
            ......:|:....|..:.:|||..:...:|...|.:.:::.|.||::.......:...:.:|:..
 Worm   132 NTSIPTSKSIALIKQIYNTCMDTEKHNAVGARDLLEKIKTYGYWPMVHNEKWRESTFDLTKLLSN 196

  Fly   306 LRLNYSEPVMIELYVGADDKNSSVNILQMDQ--LQYALPSRDYYLKESS-ANDRRAYH------- 360
            ...:....|..:.....|.:|.|..:|..||  |.....:|||||.|.. ....:||.
 Worm   197 TIQSRDVSVFFDFGPAEDSRNVSRRLLSFDQGSLGLGYSTRDYYLDEKKYEKQMKAYRKYTIGKV 261

  Fly   361 RYMTQVALLLGADPATAAAELEKVVLFETQLVNVSLPEADRHDTSLVYRKMLLPELQELVPEVQW 425
            ||.|:.| .:..:.:...:::::::.||.:...:.:.|.||.:.:.:|......:|:|.:..:.|
 Worm   262 RYYTEDA-GMAVNESKIESDVDEIIAFEKEWAQILVAEEDRRNYTKLYNVRRFDDLKEYMSIIDW 325

  Fly   426 QEYLQAALGPGIP---LQEDEPLVTYGLHYLTEMGKILAHTDRRVVHNYMLWRLVMSLMSHMIDE 487
            :: |..:..|.:.   |:.:..::...:.||.:|..:|.:||.|:|.||:|.|...|....:..:
 Worm   326 KK-LTLSTTPFLVHSYLKTNPSIIISDVEYLQKMNTLLQNTDPRIVTNYILLRWAGSWSQEIGKK 389

  Fly   488 YQRERVEFRKILMGIQSERTRWSQCVEWTNKKLGVAVGALFIRDNFNQESKEVALEMIHTIRAAF 552
            |:..:.||...:.|.:..:.||..||.....||..|.|::::|..|:..:|...|:||..::.||
 Worm   390 YEDLQQEFAFQMYGRKQRQPRWKDCVSSAGGKLSYASGSMYVRKYFDANAKNTTLDMITDLQEAF 454

  Fly   553 NELLAENDWMDDETRAVAKEKADSMNERIGYPELLTNATELEQEYVNLTIVP-DNFINNVLSILQ 616
            ..::..|||||.||:..|.||||.|.::||||:.:.|..:|:..|..|...| |:|...|...:|
 Worm   455 RNMMHANDWMDAETKKYALEKADQMLKQIGYPDFILNDEKLDDWYKGLEGAPEDSFSQLVEKSIQ 519

  Fly   617 WESEKMLRLLRQPVDKEKWTTEPAVVNAFYNPNKNDIVFPAGILQPLFYSQHFPKSLNYGGIGVV 681
            |.:....|.|.:||::.::.:..|||||||:|.:|.|.|||||||..|:...|||:|||||||.|
 Worm   520 WRNNFYYRRLLEPVNRFEFISSAAVVNAFYSPTRNAIAFPAGILQQPFFDARFPKALNYGGIGAV 584

  Fly   682 IGHEITHGFDDKGRQFDKEGNMMQWWNNATIEAFRERTQCVIDQYSRYKINEVDMFMDGRMTQGE 746
            |||||||||||.|||||..||:..||:|.|...|.|||||:|:||:..|:...|:.::|::||||
 Worm   585 IGHEITHGFDDTGRQFDNVGNLRDWWDNTTSSKFNERTQCIIEQYADVKLRGTDLRINGKLTQGE 649

  Fly   747 NIADNGGLKQAFRAYKKWETLH-GREQQLPGL-NMTHDQLFFLNYAQIWCGSMRPEDALTKIRSA 809
            |||||||:||||:|||.:...| |:|.:||.. ::|::||||:.|||:|||:..||.....:.:.
 Worm   650 NIADNGGIKQAFKAYKSYLEKHGGQEARLPQFESLTNEQLFFVGYAQVWCGAKTPETKTLLLLTD 714

  Fly   810 VHSPGFVRVLGPLSNSRDFASAYKCPLGSTMNPAEKCSVW 849
            .|||...||...|:|..:||.|:|||.||.|||.::|.||
 Worm   715 PHSPETARVNTVLTNQPEFAEAFKCPAGSPMNPTKRCVVW 754

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep1	NP_001284925.1	M13	194..847	CDD:189000	244/668 (37%)
nep-1	NP_496490.2	PepO	80..754	CDD:226118	246/675 (36%)
		M13	85..751	CDD:189000	244/667 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H56679
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG61902
OrthoDB	1	1.010	-	-		D157132at33208
OrthoFinder	1	1.000	-	-		FOG0000538
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100162
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.830