Protein Alignment Nep1 and nep-3

DIOPT Version :10

• Sequence 1: NP_511056.2
• Gene: Nep1 / 31547
• FlyBaseID: FBgn0029843
• Length: 849
• Species: Drosophila melanogaster
• Sequence 2: NP_494679.2
• Gene: nep-3 / 173730
• WormBaseID: WBGene00016778
• Length: 634
• Species: Caenorhabditis elegans
• Alignment Length: 768
• Identity: 182/768 - (23%)
• Similarity: 320/768 - (41%)
• Gaps: 180/768 - (23%)

  Fly   113 LLVLAIAFTVL--------GAAIGALAIYFASVHQRCHLYRLEPDNDDRPNGRWNQDSGSAHEGQ 169
            :::||:...|:        ...||      ..|.:.|.                |..:.||....
 Worm    16 IIILAVPIIVILPLVLLLEAGKIG------GEVSENCS----------------NHSTSSASPKP 58

  Fly   170 DNICMTQECVRTAASLLSAMDLNSDPCEDFFQYACGTWNKMHPIPEDRSSISTFEVLSDQQQVIL 234
            ..:|:|.||:.....||:..|.:.||||:|:|.|||.:|:.:.|...|:        :.:||::.
 Worm    59 KPMCLTPECITLVHQLLNFQDPSVDPCENFYQAACGKYNEHNVIDGSRT--------AQKQQIVK 115

  Fly   235 RAVLEEPIDERDNKATIKA----KTFFKSCMDIPQIRKIGTGRLKQV----LQSLGGWPVIERNW 291
            |.:.:  ...::..:|.|:    |..::.|.:...|:.:|...|.|.    :|.:|.|||::.||
 Worm   116 RLIRD--FLHKNQSSTSKSENSMKLLYEKCKEAKTIKVLGNQNLLQEIFMNIQKIGSWPVLDENW 178

  Fly   292 SPPADLSVERLMGQLRLNYSEPVMIELYVGADDKNSSVNILQMDQLQYALPSRDYYLKESSANDR 356
            ........|.|:..:||..|.....|:.:.:|   :.|.|         .|:|::..:|:.::
 Worm   179 DGKKFNLNEMLLSLIRLGVSNFGFFEIIISSD---AFVEI---------KPARNFPTRENLSD-- 229

  Fly   357 RAYHRYMTQVALLLGADPATAAAELEKVVLFETQLVNVSLPEADRHDTSLVYRKMLLPELQELVP 421
                 .:::|.|..|..|                  |::..|.|            |.|.:.|..
 Worm   230 -----IISKVFLGNGFQP------------------NITAIEND------------LREYENLQR 259

  Fly   422 EVQWQEYLQAALGPGIPLQEDEPLVTYGLHYLTEMGKILAHTDRRVVHNYMLWRLVMSLMSHMID 486
            |                              |..:.:::..|..|.:.||:::..:.|:|.
 Worm   260 E------------------------------LKSLERLIQTTPNRSLVNYLIFNYLKSVML---- 290

  Fly   487 EYQRERVEFRKILMGIQSERTRWSQCVEWTNKKLGVAVGAL-------FIRDNFNQESKEVALEM 544
            ||:|...|                ||.       ||.:..|       |:::..::|:::....|
 Worm   291 EYKRLPEE----------------QCE-------GVVIDFLPRASTRVFVQNFLDKENRKYVAGM 332

  Fly   545 IHTIRAAFNELLAENDWMDDETRAVAKEKADSMNERIGYPELLTNATELEQEYVNLTI-VPDNFI 608
            |..::..|.:::.|:.|:::|::.||.:|..::...||||:.......|::.:.:|.| ..|::.
 Worm   333 IEDVKMGFIDMIQESTWLNEESKKVAVQKVKNIKSMIGYPDFFEPPGTLDRSFKDLNIEQTDSYH 397

  Fly   609 NNVLSILQWESEKMLRLLRQ--PVDKEKWTTEPAV-VNAFYNPNKNDIVFPAGILQPLFYSQHFP 670
            ..|..|.::.:|:.:..:..  |:|..    :|.: .||||. |.|.:...|.:|....:...||
 Worm   398 TIVRKIQKFTNEQCMEFVASEIPLDPR----QPILHANAFYQ-NTNFLAILAPVLDDPIFDTTFP 457

  Fly   671 KSLNYGGIGVVIGHEITHGFDDKGRQFDKEGNMMQWWNNATIEAFRERTQCVIDQYSRYKINEVD 735
            :.:|...||.|:.|||.|.||..|..:|..|....|......|.:.:|.:|::.|:..|...:..
 Worm   458 RYVNLAVIGNVLAHEIGHAFDHTGINYDDAGQQRIWLTPEDSEEYGKRLRCLLRQHDEYDDPDFG 522

  Fly   736 MFMDGRMTQGENIADNGGLKQAFRAYKKWETLHGREQQLPGL-NMTHDQLFFLNYAQIWCGSMRP 799
            ..::|..|..|..||..|::.|:|.:||.:.  ..|.::.|. |...|||:|...|.|||   |.
 Worm   523 RNLNGSKTLHEISADRFGVEAAWRTFKKLDL--SNESEIVGFQNFNIDQLYFRTAALIWC---RQ 582

  Fly   800 EDALTKIRSAV---HSPGFVRVLGPLSNSRDFASAYKCPLGSTMNPAEKCSVW 849
            .|. |.::.|:   |.....||.|..:|...||..:.|||||.|||.:||.::
 Worm   583 RDT-TDLQYALQREHPTNNFRVNGIYANMPQFAETFNCPLGSPMNPKKKCDLF 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep1	NP_511056.2	M13	194..847	CDD:341056	164/675 (24%)
nep-3	NP_494679.2	M13	82..631	CDD:341056	163/675 (24%)