Protein Alignment Nep1 and mme

DIOPT Version :10

• Sequence 1: NP_511056.2
• Gene: Nep1 / 31547
• FlyBaseID: FBgn0029843
• Length: 849
• Species: Drosophila melanogaster
• Sequence 2: XP_031758820.1
• Gene: mme / 101734885
• XenbaseID: XB-GENE-1011098
• Length: 746
• Species: Xenopus tropicalis
• Alignment Length: 705
• Identity: 264/705 - (37%)
• Similarity: 401/705 - (56%)
• Gaps: 30/705 - (4%)

  Fly   170 DNICMTQECVRTAASLLSAMDLNSDPCEDFFQYACGTWNKMHPIPEDRSSISTFEVLSDQQQVIL 234
            |.||.:|.|:.|||.:::.||..:|||.||:|||||.|.|.:.||::....:||::|....:|:|
 Frog    47 DGICTSQACISTAARIIANMDAATDPCNDFYQYACGGWLKKNRIPDNNIVSNTFDILRTDIEVVL 111

  Fly   235 RAVLE-EPIDERDNKATIKAKTFFKSCMD--IPQIRKIGTGRLKQVLQSLGGWPVIERNWSPPAD 296
            :..|| |..|  |..|..|.|||:|||:|  |..:||  .|.|.:.|.:|..||:...||.....
 Frog   112 KDALEKESAD--DIPAIKKVKTFYKSCIDETIKNLRK--GGPLIKTLPALYDWPIAVDNWETRYG 172

  Fly   297 L--SVERLMGQLRLNYSEPVMIELYVGADDKNSSVNILQMDQLQYALPSRDYY-LKESSANDRRA 358
            |  |.:..:......|.:..:|.:||..|..|||..||.:||....|||:||| .|.:|.....|
 Frog   173 LVWSAQESIAGFITKYGQSGLINVYVSEDLTNSSTYILHIDQPGLGLPSKDYYDCKGTSEIACLA 237

  Fly   359 YHRYMTQVALL------LGADPATAAAELEKVVLFETQLVNVSLPEADRHDTSLVYRKMLLPELQ 417
            |...|..||:|      |..:.....:|:|||...|.::......|..|.:.:.:|:||.|..:.
 Frog   238 YMEQMVSVAMLIRKERNLTINEDKILSEMEKVFKLEREIAKAEASEEIRENLNDIYKKMTLSGIA 302

  Fly   418 ELVP------EVQWQEYLQAALGP-GIPLQEDEPLVTYGLHYLTEMGKILAHTDRRVVHNYMLWR 475
            :..|      .:.|.:.:.|.:.| |:.::|:|.:......||.:: :.|.....|.:.||:.||
 Frog   303 KTYPLKMNDQNINWLKLINAIISPGGVSIEENEQVALICSDYLKKL-RFLNKYKARELQNYLGWR 366

  Fly   476 LVMSLMSHMIDEYQRERVEFRKILMGIQSERTRWSQCVEWTNKKLGVAVGALFIRDNFNQESKEV 540
            .::|.::.:..||:...:..:|.|.|..:|.:.|..||.:.|..:..|:|.|::::..:.:.:.|
 Frog   367 YILSAINDLSLEYKNTGIHLKKALYGNAAEGSDWQTCVTYLNDNMEDAIGRLYLKETLSADIEHV 431

  Fly   541 AL-----EMIHTIRAAFNELLAENDWMDDETRAVAKEKADSMNERIGYPELLTNATELEQEYVNL 600
            .:     |:|..||.||.|:|.|.||||::|:..|..|..|:||||.:.|.:.:..:|.:.|..|
 Frog   432 KVKDKVKEIIAEIRRAFLEMLEEMDWMDEDTKKRAARKVASINERIAFSEDIMDDFKLNEGYSEL 496

  Fly   601 TIVPDNFINNVLSILQWESEKMLRLLRQPVDKEKWTTEPAVVNAFYNPNKNDIVFPAGILQPLFY 665
            ....|....|....:::..:||...||:.|:|.:|...||.|||||:...|:|||||||||..|:
 Frog   497 EFRVDELFENKQKYIEFVQKKMTSRLRKQVNKNEWVPGPAHVNAFYSLTYNEIVFPAGILQTPFF 561

  Fly   666 SQHFPKSLNYGGIGVVIGHEITHGFDDKGRQFDKEGNMMQWWNNATIEAFRERTQCVIDQYSRYK 730
            |...|.:|||||||::||||||||||::|..||:.||::.||.||::..|...:||.::||..|.
 Frog   562 SSSQPSALNYGGIGMIIGHEITHGFDNRGCNFDEHGNLVNWWTNASMMNFSNLSQCFVNQYGNYS 626

  Fly   731 INEV-DMFMDGRMTQGENIADNGGLKQAFRAYKKWETLHGREQQLPGLNMTHDQLFFLNYAQIWC 794
            .:|. ..:::|..|.||||:||||::.|:||:|.:...|..:..|||:::..|||||:::.||||
 Frog   627 WDEAGGQYLNGISTLGENISDNGGIRGAYRAFKNYVKSHKEDDLLPGIDLDSDQLFFISFGQIWC 691

  Fly   795 GSMRPEDALTKIRSAVHSPGFVRVLGPLSNSRDFASAYKCPLGSTMNPAEKCSVW 849
            |..|||.|.|.|::..|:||..||:|.|.||.:|:.|:.|...:.||||.||.:|
 Frog   692 GMHRPEYAATLIKTGSHTPGIFRVIGTLQNSPEFSKAFSCCNNAYMNPAVKCKLW 746

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep1	NP_511056.2	M13	194..847	CDD:341056	252/677 (37%)
mme	XP_031758820.1	M13	71..744	CDD:341056	252/677 (37%)