Protein Alignment Nep1 and mmel1

DIOPT Version :9

• Sequence 1: NP_001284925.1
• Gene: Nep1 / 31547
• FlyBaseID: FBgn0029843
• Length: 849
• Species: Drosophila melanogaster
• Sequence 2: XP_012821551.1
• Gene: mmel1 / 100145721
• XenbaseID: XB-GENE-991673
• Length: 765
• Species: Xenopus tropicalis
• Alignment Length: 696
• Identity: 284/696 - (40%)
• Similarity: 431/696 - (61%)
• Gaps: 16/696 - (2%)

  Fly   169 QDNICMTQECVRTAASLLSAMDLNSDPCEDFFQYACGTWNKMHPIPEDRSSISTFEVLSDQQQVI 233
            :::||.|..||..||.::..||...:||.||:|||||.|...|.|||..|..|.|::|.|:.::|
 Frog    71 KESICTTTGCVTAAARIIQNMDPTIEPCTDFYQYACGGWLNKHVIPETSSRYSIFDILRDEMEII 135

  Fly   234 LRAVLEEPIDERDNKATIKAKTFFKSCMDIPQIRKIGTGRLKQVLQSLGGWPVIERNW--SPPAD 296
            |:.:||.| |:.|..|..|||..:||||:...|.:..:..|.::|.::|.|||...:|  :..::
 Frog   136 LKGLLEMP-DQEDRDAFKKAKILYKSCMNESLIEQRDSLPLLELLTTVGEWPVASTDWNGTKESN 199

  Fly   297 LSVERLMGQLRLNYSEPVMIELYVGADDKNSSVNILQMDQLQYALPSRDYYL-KESSANDRRAYH 360
            .|:|..:..|...:::.|:::::|..||:.||.:|:.:||....:||||||. |.:....|.||.
 Frog   200 WSLEEKLSLLNYKFNKRVLVDIFVWNDDRESSKHIIYIDQPSLGMPSRDYYFNKGNYQRIREAYL 264

  Fly   361 RYMTQVALL------LGADPATAAAELEKVVLFETQLVNVSLPEADRHDTSLVYRKMLLPELQE- 418
            ::|..:|.:      |..|.:....|:.:|:..||.:...:.|..:|:|.:|:|.||.|.|.|:
 Frog   265 QFMITIARMVREDRNLTRDDSLVQEEMTRVMDLETDIARATAPSEERNDVTLLYNKMTLLEFQQK 329

  Fly   419 -LVPEVQWQEYLQAALGP-GIPLQEDEPLVTYGLHYLTEMGKILAHTDRRVVHNYMLWRLVMSLM 481
             .:.:..|..::|..:.. .|.||.:|.:|.||..||.::..||::.....:.||::||:|:..:
 Frog   330 FALDDFNWTSFIQGVMSSVNIQLQAEEEVVVYGAPYLHQLKNILSNYSASTLQNYVVWRMVIDRV 394

  Fly   482 SHMIDEYQRERVEFRKILMGIQSERTRWSQCVEWTNKKLGVAVGALFIRDNFNQESKEVALEMIH 546
            |.:...|:..|..:||.|.|...|..||.:||.:.|..:..||||:::::.|..|||.:..::|:
 Frog   395 SSLSRRYKDARASYRKALYGTTLEEARWRECVSYVNSNMENAVGAMYVKETFAGESKRMISDLIN 459

  Fly   547 TIRAAFNELLAENDWMDDETRAVAKEKADSMNERIGYPE--LLTNATELEQEYVNLTIVPDNFIN 609
            .:|.||.|.|.|..|||:.::..|:|||.|:.|:||||:  |.....:|:||...|......:..
 Frog   460 KVREAFIETLDELQWMDETSKDKAREKALSIKEQIGYPDYILEDQNDKLDQETAALNFSEYQYFE 524

  Fly   610 NVLSILQWESEKMLRLLRQPVDKEKWTTEPAVVNAFYNPNKNDIVFPAGILQPLFYSQHFPKSLN 674
            |:|.||...::|.|:.||:|||::.|....||.:|||:||:|.||||||||||.|:::|.|::||
 Frog   525 NILEILNSGAQKSLKKLREPVDQDAWIIGAAVADAFYSPNRNQIVFPAGILQPPFFNKHQPQALN 589

  Fly   675 YGGIGVVIGHEITHGFDDKGRQFDKEGNMMQWWNNATIEAFRERTQCVIDQYSRYKINEV-DMFM 738
            :||||:||||||||||||.||.|||:|||..||:|.:...|:::::|::.||..|..... ...:
 Frog   590 FGGIGMVIGHEITHGFDDNGRNFDKDGNMFDWWSNFSAMHFKDQSRCMVYQYGNYTWELAGGQNV 654

  Fly   739 DGRMTQGENIADNGGLKQAFRAYKKWETLHGREQQLPGLNMTHDQLFFLNYAQIWCGSMRPEDAL 803
            .|.:|.|||||||||::||::||.||...||:|.:||||::|:.||||||:||:||||.|||.|.
 Frog   655 SGIITLGENIADNGGVRQAYKAYLKWVERHGKEPKLPGLDLTYKQLFFLNFAQVWCGSYRPEYAR 719

  Fly   804 TKIRSAVHSPGFVRVLGPLSNSRDFASAYKCPLGSTMNPAEKCSVW 849
            ..|::.||||...||:|.|.|...||..:.|..|:.|:|.|||.||
 Frog   720 HSIKTDVHSPFKYRVMGSLQNFEAFAEEFNCKKGTKMHPVEKCRVW 765

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep1	NP_001284925.1	M13	194..847	CDD:189000	272/667 (41%)
mmel1	XP_012821551.1	M13	95..763	CDD:341056	272/668 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	253	1.000	Domainoid score	I2026
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	564	1.000	Inparanoid score	I1073
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D157132at33208
OrthoFinder	1	1.000	-	-		FOG0000538
OrthoInspector	1	1.000	-	-		otm49079
Panther	1	1.100	-	-	O	PTHR11733
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3535
SonicParanoid	1	1.000	-	-		X2533
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.190