DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mipp2 and RGD1564801

DIOPT Version :9

Sequence 1:	NP_511055.1	Gene:	Mipp2 / 31544	FlyBaseID:	FBgn0026060	Length:	453	Species:	Drosophila melanogaster
Sequence 2:	XP_038956737.1	Gene:	RGD1564801 / 499084	RGDID:	1564801	Length:	481	Species:	Rattus norvegicus

Alignment Length:	481	Identity:	129/481 - (26%)
Similarity:	216/481 - (44%)	Gaps:	81/481 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 LSEEGECRRLNRAD-----IEGRLSTKTPYRAIANY---DETPPK-----YAG-CHPTRIWTIIR 71
            ||....|....|.|     :.....|||.|..:..:   |...|:     .|| |.|.::..:||
  Rat    24 LSSFARCSLPGRGDPVASVLSPYFGTKTRYEDVNPWLLGDPVAPRRDPELLAGTCTPVQLVALIR 88

  Fly    72 HGTRNPSESVILQAQNRLSEIKKRILDQTKPPI-----CTAELEKLRQWH--WMHLNATEDEKLL 129
            ||||.|:...|    .:|.:::.  |.||:..:     ..|.|::...|:  ||       :..|
  Rat    89 HGTRYPTTKQI----RKLRQLQG--LLQTRESVDGGSRVAAALDQWPLWYDDWM-------DGQL 140

  Fly   130 VAEGEDELIELAERMQRRFPDLLPELYNPEWYYFKY-------TATQRTLKSAESFATGLFGRHR 187
            |.:|..::.:||.|:...||||..:        .||       ::....:.|:.:|..||:..:.
  Rat   141 VEKGRQDMRQLALRLAALFPDLFCQ--------EKYGRLRLITSSKHHCVDSSAAFLQGLWQHYH 197

  Fly   188 -------IHTVRYPPPLHEDPVLRFYKGCGKWKTDVDKNPETLVNARRFLAEPQMQSAVEQVRSS 245
                   :..:...||...|.::||:..|.|:.|:|::|...|.:...|...|:||:.:::|.::
  Rat   198 PGLPPPDVSDMECDPPRVNDKLMRFFDHCEKFLTEVERNATALYHVEAFKTGPEMQTVLKKVAAT 262

  Fly   246 TRLP--DLQPEDVQLMYTVCAFETAWHRPRHDSGSKSSYESVWCNFFDVAALEALEFFEDLEYYW 308
            .::|  :|..:.:|:.:..|:|:.|          .....|.||:.|||...:.||:..||:.||
  Rat   263 LQVPVNNLNADLIQVAFFTCSFDLA----------VQGVHSPWCDVFDVDDAKVLEYLNDLKQYW 317

  Fly   309 NDGYGYELTHRIACPAIADMFAAISSSEETRQR----RANATLYFTHSGTLLKLLAHLGLARDNK 369
            ...|||.:..|.:|....|:|..:..:.|.:||    .:...|.|.|..|||.||:.:|..:|.:
  Rat   318 KRSYGYAINSRSSCNLFQDIFLHLDKAVEQKQRSQPVSSPVILQFGHEETLLPLLSLMGYFKDKE 382

  Fly   370 PLTHKHFASE--RLWRTSQIDAFATNLAFLRYDC-DKGNP----QVLVLHQERVVRLPGCPQDKD 427
            |||..:|..:  |.:|:..|..:|:||.|:.|.| |...|    |:.:|..|:|  ||.....|.
  Rat   383 PLTAYNFEEQVHREFRSGHIVPYASNLIFVLYHCEDAQTPQEKFQIQMLLNEKV--LPLAHSQKT 445

  Fly   428 LCPLATLRRIYANSVDHCDREKMCRV 453
            :.....|:..|.:.:..|...|.|.:
  Rat   446 VALYEDLKNHYQDILQSCQTSKECNL 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mipp2	NP_511055.1	HP	68..351	CDD:299704	79/309 (26%)
RGD1564801	XP_038956737.1	HP_HAP_like	82..429	CDD:132717	103/377 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352922
Domainoid	1	1.000	140	1.000	Domainoid score	I4638
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37980
Inparanoid	1	1.050	154	1.000	Inparanoid score	I4236
OMA	1	1.010	-	-		QHG55377
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004136
OrthoInspector	1	1.000	-	-		mtm8917
orthoMCL	1	0.900	-	-		OOG6_101372
Panther	1	1.100	-	-	O	PTHR20963
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3401
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.900