Protein Alignment raptor and RAPTOR1

DIOPT Version :10

• Sequence 1: NP_572294.2
• Gene: raptor / 31543
• FlyBaseID: FBgn0029840
• Length: 1621
• Species: Drosophila melanogaster
• Sequence 2: NP_566335.1
• Gene: RAPTOR1 / 820032
• AraportID: AT3G08850
• Length: 1344
• Species: Arabidopsis thaliana
• Alignment Length: 1476
• Identity: 544/1476 - (36%)
• Similarity: 762/1476 - (51%)
• Gaps: 303/1476 - (20%)

  Fly   208 WRIRERMKTASVALVLCLNIGVDPPDVVKIQPCSRLECWIDPSSVSPPKAMELIGSNLQMQYERW 272
            ||::|||||..|||||||||.||||||:||.||:|:|.||||.|::||||:|.||.||..|||||
plant    98 WRLKERMKTGCVALVLCLNITVDPPDVIKISPCARIEAWIDPFSMAPPKALETIGKNLSTQYERW 162

  Fly   273 QPRARYKKCNDPTVDDVKKLCTSLRRNAKGERILFHYNGHGVPKPTANGEIWVFNKTFTQYIPLS 337
            |||||||...|||||:|:|||.:.|:.||.||:|||||||||||||||||||||||::||||||.
plant   163 QPRARYKVQLDPTVDEVRKLCLTCRKYAKTERVLFHYNGHGVPKPTANGEIWVFNKSYTQYIPLP 227

  Fly   338 IFELITWMSAPSIYVYDCSNAGIIINSFQPYAKQHEEELGKALAAAQQRGGVQQLVGGSGGAANV 402
            |.||.:|:..|||||:|||.|.:|:|:|   |:.|:                    .||.|::.
plant   228 ISELDSWLKTPSIYVFDCSAARMILNAF---AELHD--------------------WGSSGSSG- 268

  Fly   403 AANQVQLTNQMVSYKNCIHLAACAANEILPMNAQLPADLFTSCLTTPINIALKWYAMQEKLGMVP 467
                        |.::||.||||..:|.||.:.:.|||:|||||||||.:||||:..:..|..:
plant   269 ------------SSRDCILLAACDVHETLPQSVEFPADVFTSCLTTPIKMALKWFCRRSLLKEI- 320

  Fly   468 RIQSELIDKIPGKVNDRRTMMGELNWIFTAITDTIAWNTLPRELFQRLFRQDLLVASLFRNFLLA 532
             |...|||:|||:.|||:|::|||||||||:|||||||.||.|||||||||||||||||||||||
plant   321 -IDESLIDRIPGRQNDRKTLLGELNWIFTAVTDTIAWNVLPHELFQRLFRQDLLVASLFRNFLLA 384

  Fly   533 ERILRSHDCTPVSLPALPPCYRHPMWKAWDLVVDLALQQLPE-ILDHNAPYRQLPFFEHQLTAFQ 596
            |||:||.:|.|:|.|.|||.::|.||.|||:..::.|.|||: :||.:..::..|||..|||||:
plant   385 ERIMRSANCNPISHPMLPPTHQHHMWDAWDMAAEICLSQLPQLVLDPSTEFQPSPFFTEQLTAFE 449

  Fly   597 VWLDSESESRTPPEQLPIVLQVLLSQVHRLRALELLARFLDLGPWAVNLALGVGIFPYVLKLLQS 661
            ||||..||.:.|||||||||||||||.||.|||.||.||||:|.|||:|||.||||||||||||:
plant   450 VWLDHGSEHKKPPEQLPIVLQVLLSQCHRFRALVLLGRFLDMGSWAVDLALSVGIFPYVLKLLQT 514

  Fly   662 STRELRPVLVFIWAKILAVDPSCQVDLVKE--YKYFLSVLQDTSVSKEHRTLSAFVLSSIVHNFL 724
            :|.|||.:|||||.||||:|.|||:||||:  :.||:..|..:....|.|.::||||:.||....
plant   515 TTNELRQILVFIWTKILALDKSCQIDLVKDGGHTYFIRFLDSSGAFPEQRAMAAFVLAVIVDGHR 579

  Fly   725 LGQTSALQGPLLSICLEQLN-------DGSWLLRQWLAICLGMLWQNFEKARWSGARDLAHEKLY 782
            .||.:.|:..|:.:||..|.       ....|..|||.:|||.||::|.:|:..|....|.|||.
plant   580 RGQEACLEANLIGVCLGHLEASRPSDPQPEPLFLQWLCLCLGKLWEDFMEAQIMGREANAFEKLA 644

  Fly   783 VLLRDSIPEVRAAAVFALGTFISSVTDRS----EEQANNIDRIIA----ITMLETVGEDMSPLVR 839
            .||.:..|||||||||||||.:....|.:    |::.::.::|.|    |..|..|..|.|||||
plant   645 PLLSEPQPEVRAAAVFALGTLLDIGFDSNKSVVEDEFDDDEKIRAEDAIIKSLLDVVSDGSPLVR 709

  Fly   840 MELAAALQWMVVLFESQFVAVYLTEHMRGHVSAASFVMCPDPRDLTSSTHSLER----------- 893
            .|:|.||        ::| |....:|::  ::|||: ..|....|.:|..|:.:
plant   710 AEVAVAL--------ARF-AFGHKQHLK--LAAASY-WKPQSSSLLTSLPSIAKFHDPGSATIVS 762

  Fly   894 -HVTIRRGASSSSISNMGGASISSG-TGSS----SNPLGRSKSGSGSSGGRGAAGAAGGTNS--I 950
             |::....||:.|......:.|||. .|||    .:||....|....||....:.:.|..:.  :
plant   763 LHMSPLTRASTDSQPVARESRISSSPLGSSGLMQGSPLSDDSSLHSDSGMMHDSVSNGAVHQPRL 827

  Fly   951 PFQSIFTKLWLGICNLAQDPFPRVAAIAQEIVEHVRDTALCPIMAAKEATMANASEKCSSLSVSL 1015
            ...:::::....:..||:||.||:|::.:.::.         |:..::.             |:.
plant   828 LDNAVYSQCVRAMFALAKDPSPRIASLGRRVLS---------IIGIEQV-------------VAK 870

  Fly  1016 PPSPNTRVNYLGGGGAPGGAGATAESPPVGAAASGASHWAQKLRLSGSGACMGAGDPQTILQRKL 1080
            |..|.         |.||.|..|:.:|..|.|.|  |.|..          |.||:    |....
plant   871 PSKPT---------GRPGEAATTSHTPLAGLARS--SSWFD----------MHAGN----LPLSF 910

  Fly  1081 RTSSINDETDSGPGYSRGVAGAGT------GLGLP-SGPRESTHSARSSGSESNHYLEPGHSLTP 1138
            ||..::....:   |..|:....:      .||.| ||..:....|  ||||        .||.|
plant   911 RTPPVSPPRTN---YLSGLRRVCSLEFRPHLLGSPDSGLADPLLGA--SGSE--------RSLLP 962

  Fly  1139 IVLTEFIPWAISYFTRP--GKERYSSAEGSAEEGRQRFPVDRNSAELRRRRLRFLRNDFVRRHAG 1201
              |:....|:..:|::|  |....|....:..|.:::|.:: :.|:.:...:..|.|:
plant   963 --LSTIYGWSCGHFSKPLLGGADASQEIAAKREEKEKFALE-HIAKCQHSSISKLNNN------- 1017

  Fly  1202 RKHQELIDPYGFDVCVWNRKTQFTPSIVKLLPYEPQIAVA-YREKVLVYDFQYNSVRTYGAESLG 1265
                        .:..|:.:.:.......|.|:.|.:..| ..|::.|::::
plant  1018 ------------PIANWDTRFETGTKTALLHPFSPIVVAADENERIRVWNYE------------- 1057

  Fly  1266 GNFTGYSSGYGSGSGSSSSLNG----STPRKSGAHTSGGGGGGFSAAPFARVSSIEFINAQDMAL 1326
                           .::.|||    ..|.|.                   :|.:..||..|.:|
plant  1058 ---------------EATLLNGFDNHDFPDKG-------------------ISKLCLINELDDSL 1088

  Fly  1327 NLVAHEDGVVRVWQSSPPASSATSEDTPSKARLVTAWTALGQVNQHNHRQRSVASGGSIGKGADA 1391
            .|||..||.||:|::..         |..|.:|||.:::   :..|....|.:
plant  1089 LLVASCDGSVRIWKNYA---------TKGKQKLVTGFSS---IQGHKPGARDL------------ 1129

  Fly  1392 SGLSSAAIGSGGIVTAWQQCSQHLVIGGGGCRFIRIWDVERELKLADIPLGRSETCARVLSPYLP 1456
                       ..|..|||.|.:| ...|....:.:||:|:|..:..:|   ||:...|.:....
plant  1130 -----------NAVVDWQQQSGYL-YASGETSTVTLWDLEKEQLVRSVP---SESECGVTALSAS 1179

  Fly  1457 NMRSDVILAGCDDGSVRLFDKRCAPQDAGISVYRRHSAPILHASL------RANGL--------- 1506
            .:....:.||..|||:||:|.| :|:            |::.|:.      |..||
plant  1180 QVHGGQLAAGFADGSLRLYDVR-SPE------------PLVCATRPHQKVERVVGLSFQPGLDPA 1231

  Fly  1507 VLVSGCTEGRISVADMRGSQSSINPFDVVYEWDAGGDVTAITSHQLEDTVACGNASKIV-IYSLD 1570
            .:||....|.|...|:|.::.:....|.     ..|.:||:..|:....:|.|:|.::: ::||.
plant  1232 KVVSASQAGDIQFLDLRTTRDTYLTIDA-----HRGSLTALAVHRHAPIIASGSAKQLIKVFSLQ 1291

  Fly  1571 GRQQKVLRTNEGFIGPKIGHPTYLYFHPYKAQLAVGFVDNTVAIYS 1616
            |.|..::|....|:..|||..:.|.||||:..||.|..|:.|:||:
plant  1292 GEQLGIIRYYPSFMAQKIGSVSCLTFHPYQVLLAAGAADSFVSIYT 1337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
raptor	NP_572294.2	Raptor_N	214..365	CDD:464202	108/150 (72%)
		HEAT repeat	612..634	CDD:293787	18/21 (86%)
		HEAT repeat	646..684	CDD:293787	28/37 (76%)
		HEAT repeat	694..724	CDD:293787	11/29 (38%)
		HEAT	<725..846	CDD:441023	53/135 (39%)
		HEAT repeat	734..760	CDD:293787	10/32 (31%)
		HEAT repeat	774..803	CDD:293787	18/28 (64%)
		HEAT repeat	822..848	CDD:293787	14/29 (48%)
		WD40	1400..>1617	CDD:475233	65/233 (28%)
		WD40 repeat	1448..1489	CDD:293791	11/40 (28%)
		WD40 repeat	1496..1539	CDD:293791	11/57 (19%)
		WD40 repeat	1544..1581	CDD:293791	11/37 (30%)
		WD40 repeat	1588..1615	CDD:293791	12/26 (46%)
RAPTOR1	NP_566335.1	Raptor_N	104..255	CDD:464202	108/150 (72%)
		HEAT	635..>719	CDD:441023	36/91 (40%)
		HEAT repeat	640..667	CDD:293787	18/26 (69%)
		HEAT repeat	692..720	CDD:293787	14/36 (39%)
		WD40 repeat	1030..1067	CDD:293791	9/64 (14%)
		WD40	1035..1336	CDD:475233	94/404 (23%)
		WD40 repeat	1127..1167	CDD:293791	13/66 (20%)
		WD40 repeat	1173..1212	CDD:293791	13/51 (25%)
		WD40 repeat	1220..1257	CDD:293791	8/36 (22%)
		WD40 repeat	1264..1305	CDD:293791	11/40 (28%)