Protein Alignment CG4660 and THEM6

DIOPT Version :9

• Sequence 1: NP_572293.1
• Gene: CG4660 / 31542
• FlyBaseID: FBgn0029839
• Length: 261
• Species: Drosophila melanogaster
• Sequence 2: NP_057731.1
• Gene: THEM6 / 51337
• HGNCID: 29656
• Length: 208
• Species: Homo sapiens
• Alignment Length: 252
• Identity: 71/252 - (28%)
• Similarity: 105/252 - (41%)
• Gaps: 62/252 - (24%)

  Fly     9 LSVLLAI-IVVYGLLELHYFLRMCLCVLLARFVKRRCH-ILDTTTVNGLCLTNDVDTLLYHMNNA 71
            |..|||: :.|:.||::.|.:|:...||.||.::.|.. :|......|..|.:|:| ||.|||||
Human     5 LVALLALGLAVFALLDVWYLVRLPCAVLRARLLQPRVRDLLAEQRFPGRVLPSDLD-LLLHMNNA 68

  Fly    72 RYFRELDFARVDFYERTNLYRTITGMGGSVFQGAATIRYRRFIRPFHRFNIISRIIYWDEQSLFM 136
            ||.||.|||||....|..:...:..:.......|:..|:||.:|....|.:.:|::.||:::.::
Human    69 RYLREADFARVAHLTRCGVLGALRELRAHTVLAASCARHRRSLRLLEPFEVRTRLLGWDDRAFYL 133

  Fly   137 EHRFVRPSDKFVHCIAICRQRVIDVSMEAVMSELLPRTSSNGFRATVLTSLAAPSPAAGGISNPA 201
            |.|||...|.||..:...||.::..|.|.|:..|..|...
Human   134 EARFVSLRDGFVCALLRFRQHLLGTSPERVVQHLCQRRVE------------------------- 173

  Fly   202 MDTSLAENGHGTTSGGAAGTGATASATAAHCLKLKPSLPPELAKWIEYNDMSSKNLR 258
                                              .|.||.:|..||.||:.||:.||
Human   174 ----------------------------------PPELPADLQHWISYNEASSQLLR 196

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4660	NP_572293.1	4HBT_2	56..162	CDD:290018	38/105 (36%)
THEM6	NP_057731.1	4HBT_2	54..185	CDD:315859	47/190 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147848
Domainoid	1	1.000	92	1.000	Domainoid score	I7612
eggNOG	1	0.900	-	-		E1_KOG4366
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I4743
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59462
OrthoDB	1	1.010	-	-		D1195870at2759
OrthoFinder	1	1.000	-	-		FOG0003421
OrthoInspector	1	1.000	-	-		otm40591
orthoMCL	1	0.900	-	-		OOG6_106004
Panther	1	1.100	-	-	LDO	PTHR12475
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4781
SonicParanoid	1	1.000	-	-		X2773
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.800