DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4666 and them6

DIOPT Version :9

Sequence 1:	NP_001284923.1	Gene:	CG4666 / 31541	FlyBaseID:	FBgn0029838	Length:	193	Species:	Drosophila melanogaster
Sequence 2:	NP_001116176.1	Gene:	them6 / 569944	ZFINID:	ZDB-GENE-070912-340	Length:	205	Species:	Danio rerio

Alignment Length:	196	Identity:	75/196 - (38%)
Similarity:	114/196 - (58%)	Gaps:	16/196 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 WLV-VLLILYVIWDVNYFIRCVFTV----FAGRLFQRKRKVTDTTTIYGLCTSQDVDIFIRHMNN 62
            |:| |||:|:...||.|::|.|..|    |...:|.    ||...|..|.....|:|:.  ||||
Zfish     7 WVVGVLLLLFCTLDVWYYLRAVLVVTKAWFLSPVFD----VTGEQTASGRVVLNDIDLC--HMNN 65

  Fly    63 ARYLRELDFARFHFYALTGLYERIRDRRGGAVQGASSVRYRRTIPIFHPYKIQTKLIWWDDKAIY 127
            ||||||.||||...|...|:::.:|.....||.||:::||||.:.:...::::::::.||:|:.|
Zfish    66 ARYLRECDFARLSLYTRNGVFKALRALGATAVVGATTIRYRRPLCVGEAFELRSRIVSWDEKSFY 130

  Fly   128 LEQQFITLSDGFVRAVAMSKQNI---TNCNVLEVLKTYPETAQRPEKPEELKLWLDAIELSSQKL 189
            |||:|::..||.|.||...|||:   |...:|:.|  .....:.||.||:|:.|::.|..||:.|
Zfish   131 LEQRFVSCKDGMVSAVMFCKQNVLRSTPDKILQYL--CKRKVEVPEFPEDLQHWINFITASSKAL 193

  Fly   190 R 190
            |
Zfish   194 R 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4666	NP_001284923.1	4HBT_2	48..179	CDD:404206	51/133 (38%)
them6	NP_001116176.1	4HBT_2	53..183	CDD:290018	51/133 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581719
Domainoid	1	1.000	97	1.000	Domainoid score	I7172
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H105296
Inparanoid	1	1.050	129	1.000	Inparanoid score	I4632
OMA	1	1.010	-	-		QHG59462
OrthoDB	1	1.010	-	-		D1195870at2759
OrthoFinder	1	1.000	-	-		FOG0003421
OrthoInspector	1	1.000	-	-		mtm6532
orthoMCL	1	0.900	-	-		OOG6_106004
Panther	1	1.100	-	-	O	PTHR12475
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2773
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.910