Protein Alignment Tsp5D and CD53

DIOPT Version :10

• Sequence 1: NP_001259266.1
• Gene: Tsp5D / 31540
• FlyBaseID: FBgn0029837
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: NP_000551.1
• Gene: CD53 / 963
• HGNCID: 1686
• Length: 219
• Species: Homo sapiens
• Alignment Length: 256
• Identity: 58/256 - (22%)
• Similarity: 114/256 - (44%)
• Gaps: 46/256 - (17%)

  Fly     1 MGNAGYTCIRRTFCWLNIILWLCSCAFLGAGLWLRLSYAGYATLLPQHAGLSADTIFMGIGGTGF 65
            ||.:....::....:.|::.|:|.|..||.|::| |.:..:..|......|:...:|:.:|....
Human     1 MGMSSLKLLKYVLFFFNLLFWICGCCILGFGIYL-LIHNNFGVLFHNLPSLTLGNVFVIVGSIIM 64

  Fly    66 VVSFFGCCGAWVQSRCLLVLYFMLIVMLFMSEFLVGSIAFLFRGGLGRTLANELRFGIERHYNSS 130
            ||:|.||.|:..:::|||:.:|:|::::.::|..:..:.|::...|...:|..|...|.|:::.:
Human    65 VVAFLGCMGSIKENKCLLMSFFILLLIILLAEVTLAILLFVYEQKLNEYVAKGLTDSIHRYHSDN 129

  Fly   131 DRGSLVAPSVASIWDSVQQSFECCGVSSYEDWYDIQSWPGRRWVPESCCRTLYDQRQVLTEGSGD 195
                    |..:.|||:|...:|||::...||   .|.|     |.||
Human   130 --------STKAAWDSIQSFLQCCGINGTSDW---TSGP-----PASC----------------- 161

  Fly   196 GMMRPDCGRSENPSLWWDKGCAHSLQSWFTGQLNVVGAVGLGIAFVQLFGLITSMLLFCTV 256
                        ||....:||....:.||......:|.:.:.:..:::.|:..::.|.|.:
Human   162 ------------PSDRKVEGCYAKARLWFHSNFLYIGIITICVCVIEVLGMSFALTLNCQI 210

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp5D	NP_001259266.1	Tetraspanin	9..254	CDD:459767	55/244 (23%)
		NET-5_like_LEL	105..228	CDD:239418	27/122 (22%)
CD53	NP_000551.1	Tetraspanin	9..208	CDD:459767	55/244 (23%)
		CD53_like_LEL	104..186	CDD:239417	27/126 (21%)