Protein Alignment Tsp5D and CD9

DIOPT Version :10

• Sequence 1: NP_001259266.1
• Gene: Tsp5D / 31540
• FlyBaseID: FBgn0029837
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: NP_001400170.1
• Gene: CD9 / 928
• HGNCID: 1709
• Length: 255
• Species: Homo sapiens
• Alignment Length: 299
• Identity: 63/299 - (21%)
• Similarity: 111/299 - (37%)
• Gaps: 95/299 - (31%)

  Fly     5 GYTCIRRTFCWLNIILWLCS---------------------------CAFLGAGLWLRLSYAGYA 42
            |..||:......|.|.||.|                           .|.|..|||||.. :...
Human     6 GTKCIKYLLFGFNFIFWLKSLRVPERKAGRSGAPLFGPRPRRTVLAGIAVLAIGLWLRFD-SQTK 69

  Fly    43 TLLPQHAGLSADTIFMGI------GGTGFVVSFFGCCGAWVQSRCLLVLYFMLIVMLFMSEFLVG 101
            ::..|....:..:.:.|:      |....:|.|.|||||..:|:|:|.|:|..::::|..| :..
Human    70 SIFEQETNNNNSSFYTGVYILIGAGALMMLVGFLGCCGAVQESQCMLGLFFGFLLVIFAIE-IAA 133

  Fly   102 SIAFLFRGGLGRTLANELRFGIERHYNSS----------DRGSLVAPSVASIWDSVQQSFECCGV 156
            :|       .|.:..:|:...::..|..:          .|.:|.|         :..:..|||:
Human   134 AI-------WGYSHKDEVIKEVQEFYKDTYNKLKTKDEPQRETLKA---------IHYALNCCGL 182

  Fly   157 SSYEDWYDIQSWPGRRWVPESCCRTLYDQRQVLTEGSGDGMMRPDCGRSENPSLWWDKGCAHSLQ 221
            :                                  |..:..:...|.:.:....:..|.|..:::
Human   183 A----------------------------------GGVEQFISDICPKKDVLETFTVKSCPDAIK 213

  Fly   222 SWFTGQLNVVGAVGLGIAFVQLFGLITSMLLFCTVKHKR 260
            ..|..:.:::||||:|||.|.:||:|.||:|.|.::..|
Human   214 EVFDNKFHIIGAVGIGIAVVMIFGMIFSMILCCAIRRNR 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp5D	NP_001259266.1	Tetraspanin	9..254	CDD:459767	59/287 (21%)
		NET-5_like_LEL	105..228	CDD:239418	14/132 (11%)
CD9	NP_001400170.1	Tetraspanin	10..246	CDD:459767	59/287 (21%)
		CD9_LEL	138..220	CDD:239405	13/124 (10%)