Protein Alignment Tsp5D and TSPAN10

DIOPT Version :10

• Sequence 1: NP_001259266.1
• Gene: Tsp5D / 31540
• FlyBaseID: FBgn0029837
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: NP_114151.3
• Gene: TSPAN10 / 83882
• HGNCID: 29942
• Length: 355
• Species: Homo sapiens
• Alignment Length: 289
• Identity: 73/289 - (25%)
• Similarity: 118/289 - (40%)
• Gaps: 40/289 - (13%)

  Fly     5 GYTCIRRTFCWLNIILWLCSCAFLGAGLWLRLSYAGYATLLPQHAG-LSADTIFMGIGGTGFV-- 66
            |.:|::......|....|.....|..|||   ..|...:|.....| |.||.: :|:...|.|
Human    72 GSSCVKYLIFLSNFPFSLLGLLALAIGLW---GLAVKGSLGSDLGGPLPADPM-LGLALGGLVVS 132

  Fly    67 -VSFFGCCGAWVQSRCLL------VLYFMLIVMLFMSEFLVGSIAFLFRGGLGRTLANELRFGIE 124
             ||..|..||..::.|||      :|.|:::      |.:.|::.....|.|..:|.:.||..|
Human   133 AVSLAGYLGALCENTCLLRGFSGGILAFLVL------EAVAGALVVALWGPLQDSLEHTLRVAI- 190

  Fly   125 RHYNSSDRGSLVAPSVASIWDSVQQSFECCGVSSYEDW----YDIQSWPGRR--WVPESCCRTLY 183
            .||...       |.:..:.|.||....|||.:||:||    |...|.||.:  .:|.|||....
Human   191 AHYQDD-------PDLRFLLDQVQLGLRCCGAASYQDWQQNLYFNCSSPGVQACSLPASCCIDPR 248

  Fly   184 DQRQVLTEGSGDGMMRPDCGRSENPSLWWDKGCAHSLQSWFTGQLNVVGAVGLGIAFVQLFGLIT 248
            :....:.:..|.|::|.|...::.  :.:.:||...|:.|....|...|...:.:..:|...|:.
Human   249 EDGASVNDQCGFGVLRLDADAAQR--VVYLEGCGPPLRRWLRANLAASGGYAIAVVLLQGAELLL 311

  Fly   249 SMLLFCTVKHKRASDTYKSYSPSIDPQTR 277
            :..|...:..:|.:    :|.|....:.|
Human   312 AARLLGALAARRGA----AYGPGARGEDR 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp5D	NP_001259266.1	Tetraspanin	9..254	CDD:459767	67/260 (26%)
		NET-5_like_LEL	105..228	CDD:239418	35/128 (27%)
TSPAN10	NP_114151.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..33
		Tetraspanin	76..226	CDD:459767	46/167 (28%)
		oculospanin_like_LEL	172..291	CDD:239420	35/128 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	327..355		3/10 (30%)