Protein Alignment Tsp5D and TSPAN6

DIOPT Version :10

• Sequence 1: NP_001259266.1
• Gene: Tsp5D / 31540
• FlyBaseID: FBgn0029837
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: NP_003261.1
• Gene: TSPAN6 / 7105
• HGNCID: 11858
• Length: 245
• Species: Homo sapiens
• Alignment Length: 248
• Identity: 59/248 - (23%)
• Similarity: 105/248 - (42%)
• Gaps: 30/248 - (12%)

  Fly     7 TCIRRTFCWLNIILWLCSCAFLGAGLWLRLSYAGYATLLPQHAGLSADTIFMGIGGTGFVVSFFG 71
            ||.:........|.|:.....|..|:|.::|...|.:||.:.| .:...:.:..|....::..||
Human    15 TCFKSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNEKA-TNVPFVLIATGTVIILLGTFG 78

  Fly    72 CCGAWVQSRCLLVLYFMLIVMLFMSEFLVGSIAFLFRGGLGRTLANELRFGIERHYNSSDRGSLV 136
            |......|..:|.||.|.:.::|:.|.:...:.|:||..:..:..|.....: :.|||:  |...
Human    79 CFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEKAL-KQYNST--GDYR 140

  Fly   137 APSVASIWDSVQQSFECCGVSSYEDWYDIQSWPGRRWVPESCCRTLYDQRQVLTEGSGDGMMRPD 201
            :.:|    |.:|.:..||||:.|.||.| .::...:..|:|||:.                  .|
Human   141 SHAV----DKIQNTLHCCGVTDYRDWTD-TNYYSEKGFPKSCCKL------------------ED 182

  Fly   202 CGRSENPSLWWDKGCAHSLQSWFTGQLNVVGAVGLGIAFVQLFGLITSMLLFC 254
            |....:.....::||...:.:....::.||..:..|:|..||.|:   .|.:|
Human   183 CTPQRDADKVNNEGCFIKVMTIIESEMGVVAGISFGVACFQLIGI---FLAYC 232

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp5D	NP_001259266.1	Tetraspanin	9..254	CDD:459767	56/244 (23%)
		NET-5_like_LEL	105..228	CDD:239418	27/122 (22%)
TSPAN6	NP_003261.1	Tetraspanin	17..235	CDD:459767	57/246 (23%)
		TM4SF2_6_like_LEL	112..209	CDD:239414	27/122 (22%)