Protein Alignment Tsp5D and TSPAN7

DIOPT Version :10

• Sequence 1: NP_001259266.1
• Gene: Tsp5D / 31540
• FlyBaseID: FBgn0029837
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: NP_004606.2
• Gene: TSPAN7 / 7102
• HGNCID: 11854
• Length: 249
• Species: Homo sapiens
• Alignment Length: 270
• Identity: 69/270 - (25%)
• Similarity: 114/270 - (42%)
• Gaps: 45/270 - (16%)

  Fly     7 TCIRRTFCWLNIILWLCSCAFLGAGLWLRLSYAGYATLLPQHAGLSADTIFMGIGGTGFVVSFFG 71
            ||::......:.:.|:.....|..|:|.:|:...|.:|:.::: .:|..:.:|.|.|..|...||
Human    13 TCLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENS-TNAPYVLIGTGTTIVVFGLFG 76

  Fly    72 CCGAWVQSRCLLVLYFMLIVMLFMSEFLVGSIAFLFRGGLGRTLANELRFGIERHYNSSDRGSLV 136
            |......|..:|.||.|.:.::|::|.:.|...|:||..:..|........::. ||.:|..|..
Human    77 CFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQT-YNGNDERSRA 140

  Fly   137 APSVASIWDSVQQSFECCGVSSYEDW----YDIQSWPGRRWVPESCCRTLYDQRQVLTEGSGDGM 197
            .       |.||:|..||||.:|.:|    |.::     ..:|.|||                 |
Human   141 V-------DHVQRSLSCCGVQNYTNWSTSPYFLE-----HGIPPSCC-----------------M 176

  Fly   198 MRPDCGRSENPSLWW------DKGCAHSLQSWFTGQLNVVGAVGLGIAFVQLFGLITSMLLFCTV 256
            ...||...:..:|..      .|||...:.|:....:.::..|..||||.||.|    |||.|.:
Human   177 NETDCNPQDLHNLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIG----MLLACCL 237

  Fly   257 KHKRASDTYK 266
            .....::.|:
Human   238 SRFITANQYE 247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp5D	NP_001259266.1	Tetraspanin	9..254	CDD:459767	65/254 (26%)
		NET-5_like_LEL	105..228	CDD:239418	31/132 (23%)
TSPAN7	NP_004606.2	Tetraspanin	15..239	CDD:459767	66/258 (26%)
		TM4SF2_6_like_LEL	110..213	CDD:239414	31/132 (23%)