Protein Alignment Tsp5D and Tspan1

DIOPT Version :10

• Sequence 1: NP_001259266.1
• Gene: Tsp5D / 31540
• FlyBaseID: FBgn0029837
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: NP_598442.1
• Gene: Tspan1 / 66805
• MGIID: 1914055
• Length: 240
• Species: Mus musculus
• Alignment Length: 254
• Identity: 57/254 - (22%)
• Similarity: 113/254 - (44%)
• Gaps: 41/254 - (16%)

  Fly    17 NIILWLCSCAFLGAGLWLRLSYAGYATLLPQHAGLSADTI-FMGIG----GTG---FVVSFFGCC 73
            |::::||..|.|..|:|:.:....:   |.....||:..: |:.:|    ..|   |::.|.||.
Mouse    15 NLLIFLCGAALLAVGIWVSVDGTSF---LKVFGSLSSSAMQFVNVGYFLIAAGAVLFILGFLGCY 76

  Fly    74 GAWVQSRCLLVLYFMLIVMLFMSEFLVGSIAFLFRGGLGRTLANELRF-----GIERHYNSSDRG 133
            ||..:::|:|:::|.:::::|::|.....:|.::     .|||.:...     .||:.|.
Mouse    77 GAHSENKCVLMMFFSILLIIFIAEIAGAVVALVY-----TTLAEQFLTLLVVPAIEKDYG----- 131

  Fly   134 SLVAPSVASIWDSVQQSFECCGVSSYEDWYDIQSWPGRRWVPESCCRTLYDQRQVLTEGSGDGMM 198
              .......:|::..:...|||.::|.|:...:.....:..|..||           ...|:..:
Mouse   132 --YQTDFTQVWNTTMEELHCCGFNNYTDFNASRFVKENKVFPPPCC-----------ANPGNHTV 183

  Fly   199 RPDCGRSENPSLWWDKGCAHSLQSWFTGQLNVVGAVGLGIAFVQLFGLITSMLLFCTVK 257
            .| |...:..|: ..:||...:..........||.|.:|:|.::|..::.||.|:|.:|
Mouse   184 EP-CTEEKAKSM-KVQGCFKEILHRIRANAVTVGGVAVGVAALELAAMVVSMYLYCNLK 240

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp5D	NP_001259266.1	Tetraspanin	9..254	CDD:459767	55/249 (22%)
		NET-5_like_LEL	105..228	CDD:239418	21/127 (17%)
Tspan1	NP_598442.1	Tetraspanin	7..>151	CDD:459767	33/150 (22%)
		uroplakin_I_like_LEL	106..208	CDD:239409	22/126 (17%)