Protein Alignment Tsp5D and CD82

DIOPT Version :10

• Sequence 1: NP_001259266.1
• Gene: Tsp5D / 31540
• FlyBaseID: FBgn0029837
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: XP_047282856.1
• Gene: CD82 / 3732
• HGNCID: 6210
• Length: 308
• Species: Homo sapiens
• Alignment Length: 284
• Identity: 80/284 - (28%)
• Similarity: 133/284 - (46%)
• Gaps: 38/284 - (13%)

  Fly     2 GNAGYTCIRRT--FCWL-NIILWLCSCAFLGAGLWLRLSYAGYATLLPQHAGLS---ADTIFMGI 60
            |..|..||:.|  |.:| |:|.::.....||.|:|:....:.:.::| |.:..|   ...:|:|:
Human    40 GGMGSACIKVTKYFLFLFNLIFFILGAVILGFGVWILADKSSFISVL-QTSSSSLRMGAYVFIGV 103

  Fly    61 GGTGFVVSFFGCCGAWVQSRCLLVLYFMLIVMLFMSEFLVGSIAFLFRGGLGRTLANELRFGIE- 124
            |....::.|.||.||..:.||||.|||..::::.:::...|::.:...|.|.:.:.     ||.
Human   104 GAVTMLMGFLGCIGAVNEVRCLLGLYFAFLLLILIAQVTAGALFYFNMGKLKQEMG-----GIVT 163

  Fly   125 ---RHYNSSDRGSLVAPSVASIWDSVQQSFECCGVSSYEDWYDIQSWPGRRWVPESC-CRTLYDQ 185
               |.||||...||     ...||.||...:|||..|:.:|.|......|..|...| |....::
Human   164 ELIRDYNSSREDSL-----QDAWDYVQAQVKCCGWVSFYNWTDNAELMNRPEVTYPCSCEVKGEE 223

  Fly   186 ------RQVLTEGSGDGMMRPDCGRSENPSLW--WDKGCAHSLQSWFTGQLNVVGAVGLGIAFVQ 242
                  |:...|..|:   |...|  .:|..|  :.:||...:|:|....|.::..||:|:|.::
Human   224 DNSLSVRKGFCEAPGN---RTQSG--NHPEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVAIIE 283

  Fly   243 LFGLITSMLLFCTVKHKRASDTYK 266
            |.|::.|:   |..:|..:.|..|
Human   284 LLGMVLSI---CLCRHVHSEDYSK 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp5D	NP_001259266.1	Tetraspanin	9..254	CDD:459767	73/263 (28%)
		NET-5_like_LEL	105..228	CDD:239418	36/135 (27%)
CD82	XP_047282856.1	Tetraspanin	65..295	CDD:459767	68/248 (27%)
		CD37_CD82_like_LEL	147..270	CDD:239413	36/137 (26%)