Protein Alignment Tsp5D and Cd37

DIOPT Version :10

• Sequence 1: NP_001259266.1
• Gene: Tsp5D / 31540
• FlyBaseID: FBgn0029837
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: XP_017444339.1
• Gene: Cd37 / 29185
• RGDID: 62035
• Length: 396
• Species: Rattus norvegicus
• Alignment Length: 275
• Identity: 59/275 - (21%)
• Similarity: 98/275 - (35%)
• Gaps: 81/275 - (29%)

  Fly    31 GLWLRLSYAGYATLLPQHAGLSADTI-----FMGIGGT-GFVVSFFGCCGAWVQSRCLLVLYFML 89
            |.|:.:....:.:.:    |||...:     .:.:.|. ...::..||.||..:.||||.|||.:
  Rat    56 GTWILIDKTSFVSFV----GLSFVPLQTWSKVLSVSGVLTMALALLGCVGALKELRCLLGLYFGM 116

  Fly    90 IVMLFMSEFLVGSIAFLFRGGLGRTLANELRFGIERHYNSSDRGSLVAPSVASIWDSVQQSFECC 154
            :::||.::..:|.:....|..|.|.:...:...|:.:..:.|.     .:....||..|....||
  Rat   117 LLLLFATQITLGILISTQRVRLERRVQELVLRTIQSYRTNPDE-----TAAEESWDYAQFQLRCC 176

  Fly   155 GVSSYEDWYDIQSWPGRRWVPESCCRTLYDQRQVLTEGSGDGMMRP-DCGRS--ENPSLWWDK-- 214
            |..|..||                     ::.|:|.....:.:..| .|..|  .|.|..:||
  Rat   177 GWQSPRDW---------------------NKAQMLKANGSEELFVPCSCYNSTATNDSSGFDKLF 220

  Fly   215 -------------------------------GCAHSLQSWFTGQLNVVGAVG--LGIAFVQLFGL 246
                                           |||.|||.|...  |::..||  ||:..:::.|
  Rat   221 LSQLSRLGPRAKLRQTADICALPAKAHIYREGCARSLQKWLHN--NIISIVGICLGVGLLEVSG- 282

  Fly   247 ITSMLLFCTVKHKRA 261
                :..|....:||
  Rat   283 ----MALCLQLQRRA 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp5D	NP_001259266.1	Tetraspanin	9..254	CDD:459767	56/266 (21%)
		NET-5_like_LEL	105..228	CDD:239418	30/158 (19%)
Cd37	XP_017444339.1	Tetraspanin	49..>177	CDD:459767	29/129 (22%)
		CD37_CD82_like_LEL	131..266	CDD:239413	31/162 (19%)