Protein Alignment Tsp5D and TSPAN17

DIOPT Version :10

• Sequence 1: NP_001259266.1
• Gene: Tsp5D / 31540
• FlyBaseID: FBgn0029837
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: NP_001353420.1
• Gene: TSPAN17 / 26262
• HGNCID: 13594
• Length: 355
• Species: Homo sapiens
• Alignment Length: 323
• Identity: 71/323 - (21%)
• Similarity: 120/323 - (37%)
• Gaps: 69/323 - (21%)

  Fly     8 CIRRTFCW-LNIILWLCSCAFLGAGLWL--RLSYAGYATLLPQHAGLSADTIFMGIGGTGFVVSF 69
            |..:.|.: .||:.|:....||..|||.  ........:.|....||....:|:.:||...|:.|
Human    15 CCGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMSVLGF 79

  Fly    70 FGCCGAWVQSRCLLVLYFMLIVMLFMSEFLVGSIAFLFRGGLGRTLANELRFGIERHYNSSDRGS 134
            .||.||..::..||..:.:.:.::|..|...|.:||:|:..:...|...:...::.:.:..|..:
Human    80 AGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKAYRDDIDLQN 144

  Fly   135 LVAPSVASIWDSVQQSFECCGVSSYEDW--------YDIQSWPGRRWVPESCCRTLYDQRQVLTE 191
            |:        |..|:.:.|||.....||        .|:.....|..||.|||          ..
Human   145 LI--------DFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCC----------VR 191

  Fly   192 GSGDGMMRPDCG-------RSENPSLWWDKGCAHSLQSWFTGQLNVVGAVGLGIAF--------- 240
            ...:.::...||       ..|.......|||....:.|....|.||..|.:|||.
Human   192 DPAEDVLNTQCGYDVRLKLELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQVPLWPHV 256

  Fly   241 -----------------VQLFGLITSMLLFCTVKHKRA-----SDTYKSY--SPSIDPQTRTS 279
                             :|:||:..:..|...:|..:|     :|.::::  :|:|.....|:
Human   257 PLPLPGPPSLSPHLSSVLQIFGICLAQNLVSDIKAVKANWSKWNDDFENHWLTPTISEVLSTA 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp5D	NP_001259266.1	Tetraspanin	9..254	CDD:459767	64/288 (22%)
		NET-5_like_LEL	105..228	CDD:239418	26/137 (19%)
TSPAN17	NP_001353420.1	Tetraspanin	18..>157	CDD:459767	35/146 (24%)
		TM4SF9_like_LEL	115..235	CDD:239412	26/137 (19%)