Protein Alignment Tsp5D and Prph2

DIOPT Version :10

• Sequence 1: NP_001259266.1
• Gene: Tsp5D / 31540
• FlyBaseID: FBgn0029837
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: NP_037153.1
• Gene: Prph2 / 25534
• RGDID: 3549
• Length: 346
• Species: Rattus norvegicus
• Alignment Length: 303
• Identity: 69/303 - (22%)
• Similarity: 120/303 - (39%)
• Gaps: 57/303 - (18%)

  Fly    15 WLNIILWLCSCAFLGAGLWLRLSYAGYATLLPQHAGLSADTIFMGIGGTGFVVSFFG---CCGA- 75
            ||::   |........||:|::.....:.::............:|:|....|.:...   |..|
  Rat    25 WLSV---LAGIVLFSLGLFLKIELRKRSDVMDNSESHFVPNSLIGVGVLSCVFNSLAGKICYDAL 86

  Fly    76 ----WVQSRCLLVLYFMLIVMLFMSEFLVGSIAFLFRGGLGRTLANELRFGIERHYNSSDRGSLV 136
                :.:.:..|.||..:.|...:..|||....||.||.|..|||..|:.|: ::|..:|
  Rat    87 DPAKYAKWKPWLKLYLAVCVFFNVILFLVALCCFLLRGSLESTLAYGLKNGM-KYYRDTD----- 145

  Fly   137 APS---VASIWDSVQQSFECCGVSSYEDWYDIQSWPGRRW------------------------V 174
            .|.   :....|.:|..|:|||.:.:.||::|| |...|:                        |
  Rat   146 TPGRCFMKKTIDMLQIEFKCCGNNGFRDWFEIQ-WISNRYLDFSSKEVKDRIKSNVDGRYLVDGV 209

  Fly   175 PESCCRTLYDQRQVLTEGSGDGMMRPDCGRSENPSLWWDKGCAHSLQSWFTGQLNVVGAVGLGIA 239
            |.|||.....:..:..:.:.:........::|..:||. :||..:|.::::..:|.:|.|.|
  Rat   210 PFSCCNPSSPRPCIQYQLTNNSAHYSYDHQTEELNLWL-RGCRAALLNYYSSLMNSMGVVTL--- 270

  Fly   240 FVQLFGL-ITSMLLFCTVKHKRASDTYKSYSPSIDPQTRTSSW 281
            .:.||.: ||:.|.|       .....:|.|...||:..:..|
  Rat   271 LIWLFEVSITAGLRF-------LHTALESVSNPEDPECESEGW 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp5D	NP_001259266.1	Tetraspanin	9..254	CDD:459767	63/274 (23%)
		NET-5_like_LEL	105..228	CDD:239418	36/149 (24%)
Prph2	NP_037153.1	Tetraspanin	16..181	CDD:459767	42/165 (25%)
		peripherin_like_LEL	120..262	CDD:239415	36/149 (24%)
		Interaction with MREG. /evidence=ECO:0000250	341..346