Protein Alignment Tsp5D and tsp-17

DIOPT Version :10

• Sequence 1: NP_001259266.1
• Gene: Tsp5D / 31540
• FlyBaseID: FBgn0029837
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: NP_001129920.2
• Gene: tsp-17 / 192067
• WormBaseID: WBGene00006643
• Length: 312
• Species: Caenorhabditis elegans
• Alignment Length: 325
• Identity: 69/325 - (21%)
• Similarity: 108/325 - (33%)
• Gaps: 100/325 - (30%)

  Fly     5 GYTCIRRTFCWLNIILWLCSCAFLGAGLWLRLS-----------YAGYATLLPQHAGLSADTIFM 58
            |..|:|......:|..||.:...:..|||:.|.           ::....||...|.:|     :
 Worm     7 GGGCLRVAVSIFSIYYWLSALGHVFLGLWMLLDPKRNYILDLVHFSENDPLLKASAYVS-----L 66

  Fly    59 GIGGTGFVVSFFGCCGAWVQSRCLLVLYFMLIVMLFMSEFLVGSIAFLFR-----GGLGRTLANE 118
            ..|....:|.|.|.|||..:||.||:.:.|.::..|:::..:|:::..::     ..:|..|.|
 Worm    67 VCGCAQLLVGFLGLCGAVNRSRFLLLAFVMFLIGTFLADVAMGTLSLFYKDKFSNNYMGVYLKN- 130

  Fly   119 LRFGIERHYNSSDRGSLVAP----------------------------------SVASIWDSVQQ 149
                  ..||...|...|.|                                  .|....|.:|.
 Worm   131 ------LTYNRYSRDRWVLPLMDTIQFYVYSVKENVREIVKSKYGVMTSEPENKMVTEFIDKLQF 189

  Fly   150 SFECCGVSSYEDWYDIQSWPGRRW---------------VPESCCRTLYDQRQVLTEGSGDGMMR 199
            ..:|||.....|:  |.|    ||               .|.|||          |:.:|...:.
 Worm   190 YEKCCGSLGPTDY--ISS----RWSQSTNQDSEEIESPLFPVSCC----------TQITGASALN 238

  Fly   200 P------DCGRSENPSLWWDK-GCAHSLQSWFTGQLNVVGAVGLGIAFVQLFGLITSMLLFCTVK 257
            |      .|.:......|... ||:..|.|||..|:.:....|.|.|...:.|:..|..|...::
 Worm   239 PLAKSYARCQQIGANRQWRHAVGCSERLMSWFNEQIWIFVGFGFGSALTMMLGICLSCCLISKIR 303

  Fly   258  257
             Worm   304  303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp5D	NP_001259266.1	Tetraspanin	9..254	CDD:459767	67/316 (21%)
		NET-5_like_LEL	105..228	CDD:239418	34/183 (19%)
tsp-17	NP_001129920.2	Tetraspanin	11..>150	CDD:459767	34/150 (23%)
		CD37_CD82_like_LEL	153..275	CDD:239413	27/137 (20%)