Protein Alignment Tsp5D and tsp-8

DIOPT Version :10

• Sequence 1: NP_001259266.1
• Gene: Tsp5D / 31540
• FlyBaseID: FBgn0029837
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: NP_510445.1
• Gene: tsp-8 / 181567
• WormBaseID: WBGene00006634
• Length: 282
• Species: Caenorhabditis elegans
• Alignment Length: 292
• Identity: 69/292 - (23%)
• Similarity: 113/292 - (38%)
• Gaps: 63/292 - (21%)

  Fly     7 TCIRR----TFCWLNIILWLCSCAFLGAGLWLRLSYAG--YATLLPQHAGL--SADTIFMGIGGT 63
            :|:..    ||.: |...||......|.|:||....|.  :..|...|.|.  ......:|.|..
 Worm     3 SCVNALRIVTFLF-NFAFWLSGVVVFGLGIWLLFDPAASDFFALHSTHPGAFRYVGWFLVGAGAI 66

  Fly    64 GFVVSFFGCCGAWVQSRCLLVLYFMLIVMLFMSEFLVGSIAFLFRGGLGRTLANELRFGIERHYN 128
            ..:|.:|||.|||..::|.|..:..::::.|..|.......|..:..:...:.:.:...|...|:
 Worm    67 IILVGYFGCIGAWKMNQCALAFFCCILILAFFLELAAAVTLFHKQEHIKHYVESSMYDTIRNRYS 131

  Fly   129 SSDRGSLVAPSVASIWDSVQQSFECCGVSSYEDW------------------------YDIQSWP 169
            |.       .:....:|:||:.||||||.:|.||                        :.|.::.
 Worm   132 SE-------TAFKDAFDTVQEKFECCGVKTYTDWLSARWDAEPSTQLEVNEEDAGRIEHGIGAFG 189

  Fly   170 GRRW-----VPESCCRTLYDQRQVLTEGSGDGMMRPDCGR--SENPSLWW-----DKGCAHSLQS 222
            |.:.     ||.|||..           .|......:|||  |:.|...:     .:|||.::..
 Worm   190 GNKGTGYGRVPSSCCNE-----------HGKLSYPNNCGRSFSQAPLNTYAQFINTRGCADAVYE 243

  Fly   223 WFTGQLNVVGAVGLGIAFVQLFGLITSMLLFC 254
            ..:..|:::..|.:.:..|||.|::.||.|.|
 Worm   244 SVSSSLSLIVGVCVVLCIVQLLGIVLSMTLCC 275

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp5D	NP_001259266.1	Tetraspanin	9..254	CDD:459767	67/288 (23%)
		NET-5_like_LEL	105..228	CDD:239418	32/158 (20%)
tsp-8	NP_510445.1	Tetraspanin	8..>151	CDD:459767	36/150 (24%)
		tetraspanin_LEL	108..243	CDD:239401	32/152 (21%)