Protein Alignment Tsp5D and tsp-14

DIOPT Version :10

• Sequence 1: NP_001259266.1
• Gene: Tsp5D / 31540
• FlyBaseID: FBgn0029837
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: NP_001367834.1
• Gene: tsp-14 / 180761
• WormBaseID: WBGene00006640
• Length: 451
• Species: Caenorhabditis elegans
• Alignment Length: 298
• Identity: 80/298 - (26%)
• Similarity: 122/298 - (40%)
• Gaps: 77/298 - (25%)

  Fly     8 CIRRTFCWLNIILWLCSCAFLGAGLWLRLSYAGYATLLPQHAGLSADTIFMGIGGTGF-VVSFFG 71
            |::.....||.|::|.....|..|::|.:.......|:..   :....|.:.|.|... ||||||
 Worm    53 CLKWLVFLLNSIVFLVGVGILALGVYLFIKDFREVKLVDI---ILNPAILISIFGFSICVVSFFG 114

  Fly    72 CCGAWVQSRCLLVLYFMLIVMLFMSEFLVGSIAFLF--------RGGLGRTLANELRFGIERHYN 128
            ..|| ::....|:..|...|  |:|..||.::..:|        ..||.   ||.|.....::|:
 Worm   115 FMGA-LRDNIFLLKCFAACV--FLSYILVVAVTLVFFTLFYTDTTEGLS---ANWLLLYAVKNYH 173

  Fly   129 SSDRGSLVAPSVASIWDSVQQSFECCGVSS----YEDW---YDI-----QSWPGRRWVPESCCRT 181
            ::       .::|.|.|::|::.|||||||    |.||   |..     ...|.:..||.||||
 Worm   174 TN-------RNLAEIMDALQENLECCGVSSIAQGYRDWNMSYQFNCTNSNPQPEKCGVPFSCCR- 230

  Fly   182 LYDQRQVLTEGSGDGMMRPDCGRSENPSL--------W---------------WDKGCAHSLQSW 223
                :.|::|.:|          |.||.|        |               :.:||...|::.
 Worm   231 ----KSVISEAAG----------SSNPLLPAMRSLECWQNALTKRPGDLEHDIYTRGCLQPLRTL 281

  Fly   224 FTGQLNVVGA-VGLGIAFVQLFGLITSMLLFCTVKHKR 260
            |......||| |.|.|..|.:...:|: :|...|.|:|
 Worm   282 FESHAVHVGAFVALLIVPVCISVCLTN-ILAKQVDHQR 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp5D	NP_001259266.1	Tetraspanin	9..254	CDD:459767	76/289 (26%)
		NET-5_like_LEL	105..228	CDD:239418	41/165 (25%)
tsp-14	NP_001367834.1	Tetraspanin	54..>193	CDD:459767	39/154 (25%)
		tetraspanin_LEL	145..286	CDD:351888	41/165 (25%)