Protein Alignment Tsp5D and Tspan8

DIOPT Version :10

• Sequence 1: NP_001259266.1
• Gene: Tsp5D / 31540
• FlyBaseID: FBgn0029837
• Length: 287
• Species: Drosophila melanogaster
• Sequence 2: NP_598210.1
• Gene: Tspan8 / 171048
• RGDID: 621783
• Length: 235
• Species: Rattus norvegicus
• Alignment Length: 256
• Identity: 65/256 - (25%)
• Similarity: 115/256 - (44%)
• Gaps: 31/256 - (12%)

  Fly     8 CIRRTFCWLNIILWLCSCAFLGAGLWLRLSYAGYATLLPQHAGLS---ADTIFMGIGGTGFVVSF 69
            |::.:..:.|.:.|:|....||..:|||:|..|...:.....|.:   |..|.:.:|....|:.|
  Rat     7 CLKYSMFFFNFLFWVCGTLILGLAIWLRVSKDGKEIITSGDNGTNPFIAVNILIAVGSIIMVLGF 71

  Fly    70 FGCCGAWVQSRCLLVLYFMLIVMLFMSEFLVGSIAFLFRGGLGRTLANELRFGIERHYNSSDRGS 134
            .|||||..:|||:|:|:|:.::::.:.:...|.:...|:....|.|...|....:....:|:.
  Rat    72 LGCCGAVKESRCMLLLFFIGLLLILLLQVAAGILGATFKSESSRILNETLYENAKLLSETSNE-- 134

  Fly   135 LVAPSVASIWDSVQQSFECCGVS-SYEDWYDIQSWPGRRWVPESCCRTLYDQRQVLTEGSGDGMM 198
              |..|.....:.|..|:|||:. ...||.  :::|..:   |||..|          ||
  Rat   135 --AKEVQKAMIAFQSEFKCCGLRFGAADWG--KNFPDAK---ESCQCT----------GS----- 177

  Fly   199 RPDCGRSENPSLWWDKGCAHSLQSWFTGQLNVVGAVGLGIAFVQLFGLITSMLLFCTVKHK 259
              || .|.|....:...|...::......:.:|..:..|:|.:::.||:.||:|:|.:..|
  Rat   178 --DC-ESYNGENVYRTTCLSLIKELVEKNIIIVIGIAFGLAVIEILGLVFSMVLYCQIGSK 235

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp5D	NP_001259266.1	Tetraspanin	9..254	CDD:459767	62/248 (25%)
		NET-5_like_LEL	105..228	CDD:239418	26/123 (21%)
Tspan8	NP_598210.1	Tetraspanin	8..230	CDD:459767	62/248 (25%)
		TM4SF3_like_LEL	106..204	CDD:239407	26/124 (21%)