DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tsp5D and LOC100492951

DIOPT Version :9

Sequence 1:	NP_001259266.1	Gene:	Tsp5D / 31540	FlyBaseID:	FBgn0029837	Length:	287	Species:	Drosophila melanogaster
Sequence 2:	XP_002936078.2	Gene:	LOC100492951 / 100492951	-ID:	-	Length:	330	Species:	Xenopus tropicalis

Alignment Length:	258	Identity:	73/258 - (28%)
Similarity:	127/258 - (49%)	Gaps:	29/258 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 CIRRTFCWLNIILWLCSCAFLGAGLWLRLSYAGYATLLPQHAGLSADTIFMGIGGTGFVVSFFGC 72
            |::......|::.||..|..||.|:||.::...:|||......|||..|.:..|....:|.|.||
Frog   100 CMKYLMFVFNLLFWLGGCGILGVGIWLAVTQGNFATLSSSFPSLSAANILIATGTIVMIVGFLGC 164

  Fly    73 CGAWVQSRCLLVLYFMLIVMLFMSEFLVGSIAFLFRGGLGRTLANELRFGIERHYNSSDRGSLVA 137
            .||..:::.||:.:|:|::::|:.|.:|.::.|::...:.|....:|:.|:..:....:.|
Frog   165 IGAIKENKYLLLSFFILLLIIFLLELIVVTLFFIYTDKIDRYAQQDLKKGLHLYGTEGNIG---- 225

  Fly   138 PSVASIWDSVQQSFECCGVSSYEDWYDIQSWPGRRWVPESCCRTLYDQRQVLTEGSGDGMMRPDC 202
              :.:.|..:|..|.||||::|.||:::.:   ...||:|||....:                :|
Frog   226 --LTNAWSIIQTDFRCCGVANYTDWFEVYN---ATRVPDSCCLEFSE----------------NC 269

  Fly   203 GRSENPSLWWDKGCAHSLQSWFTGQLNVVGAVGLGIAFVQLFGLITSMLLFCTVKHKRASDTY 265
            | ..:|..||...|..:::.|....|..||..||..|.||:.||..:|.::|.:   ..:|||
Frog   270 G-LHSPGTWWKSPCYDTVKIWLHENLLAVGIFGLCTALVQILGLTFAMTMYCQM---AKTDTY 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tsp5D	NP_001259266.1	Tetraspannin	8..256	CDD:278750	70/247 (28%)
Tsp5D	NP_001259266.1	NET-5_like_LEL	105..228	CDD:239418	27/122 (22%)
LOC100492951	XP_002936078.2	Tetraspannin	102..318	CDD:366035	68/241 (28%)
LOC100492951	XP_002936078.2	NET-5_like_LEL	197..294	CDD:239418	27/122 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	143	1.000	Domainoid score	I4608
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	149	1.000	Inparanoid score	I4273
OMA	1	1.010	-	-		QHG45282
OrthoDB	1	1.010	-	-		D1224210at2759
OrthoFinder	1	1.000	-	-		FOG0001172
OrthoInspector	1	1.000	-	-		otm48583
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X124
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.980