DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tsp5D and tspan9

DIOPT Version :9

Sequence 1:	NP_001259266.1	Gene:	Tsp5D / 31540	FlyBaseID:	FBgn0029837	Length:	287	Species:	Drosophila melanogaster
Sequence 2:	XP_012813987.1	Gene:	tspan9 / 100144960	XenbaseID:	XB-GENE-956624	Length:	326	Species:	Xenopus tropicalis

Alignment Length:	261	Identity:	79/261 - (30%)
Similarity:	130/261 - (49%)	Gaps:	31/261 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 CIRRTFCWLNIILWLCSCAFLGAGLWLRLSYAGYATLLPQHAGLSADTIFMGIGGTGFVVSFFGC 72
            |::......|:|.|||.|..||.|:||.:|...:||..|....|||..:.:.||....|..|.||
Frog    95 CLKYMMFLFNLIFWLCGCGLLGVGIWLSVSQGNFATFSPSFPSLSAANLVIAIGTIVMVTGFLGC 159

  Fly    73 CGAWVQSRCLLVLYFMLIVMLFMSEFLVGSIAFLFRGGLGRTLANELRFGIERHYNSSDRGSLVA 137
            .||..:::|||:.:|::::::.::|.::..:.|::...:......:|:.|: ..||:.:...|
Frog   160 LGAIKENKCLLLSFFIILLIILLAELILLILFFVYMDKVNENAKQDLKDGL-LLYNTENNVGL-- 221

  Fly   138 PSVASIWDSVQQSFECCGVSSYEDWYDIQSWPGRRWVPESCCRTLYDQRQVLTEGSGDGMMRPDC 202
               .:.|:.:|....||||:.|.|||.:.   |...||:.||          .|.|      .||
Frog   222 ---KNAWNIIQAEMHCCGVTDYTDWYPVL---GENTVPDRCC----------MENS------QDC 264

  Fly   203 GRSENPSLWWDKGCAHSLQSWFTGQLNVVGAVGLGIAFVQLFGLITSMLLFCTVKHKRASDTYKS 267
            |.: :.||.|..||...::.||....:|:|.:|:.|..:|:.|:..||.||..: |:    |.|.
Frog   265 GHN-STSLVWKTGCYEKVKMWFDDNKHVLGTIGMCILIIQILGMAFSMTLFQQI-HR----TGKK 323

  Fly   268 Y 268
            |
Frog   324 Y 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tsp5D	NP_001259266.1	Tetraspannin	8..256	CDD:278750	75/247 (30%)
Tsp5D	NP_001259266.1	NET-5_like_LEL	105..228	CDD:239418	33/122 (27%)
tspan9	XP_012813987.1	Tetraspannin	96..313	CDD:366035	72/242 (30%)
tspan9	XP_012813987.1	NET-5_like_LEL	192..289	CDD:239418	33/122 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	143	1.000	Domainoid score	I4608
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4860
Inparanoid	1	1.050	149	1.000	Inparanoid score	I4273
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1224210at2759
OrthoFinder	1	1.000	-	-		FOG0001172
OrthoInspector	1	1.000	-	-		otm48583
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6363
SonicParanoid	1	1.000	-	-		X124
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	11.000