Protein Alignment CG5921 and SLC9A3R1

DIOPT Version :9

• Sequence 1: NP_727061.2
• Gene: CG5921 / 31538
• FlyBaseID: FBgn0029835
• Length: 886
• Species: Drosophila melanogaster
• Sequence 2: NP_004243.1
• Gene: SLC9A3R1 / 9368
• HGNCID: 11075
• Length: 358
• Species: Homo sapiens
• Alignment Length: 312
• Identity: 72/312 - (23%)
• Similarity: 120/312 - (38%)
• Gaps: 89/312 - (28%)

  Fly    80 ERG-STYGFTVRGGREHG-TGFFVSHVEHGGEAHLKGLRIGDQILRINGFRLDDAVHKEFIQLVA 142
            |:| :.|||.:.|  |.| .|.::..||.|..|...||..||:::.:||..::...|::.:
Human    18 EKGPNGYGFHLHG--EKGKLGQYIRLVEPGSPAEKAGLLAGDRLVEVNGENVEKETHQQVV---- 76

  Fly   143 GQDRVTLKVRGVGMLPVRDLPEERLSWSVVKL----------PSVSGTPSESSFKG-----ERRG 192
              .|:...:..|.:|.|....:|:|....|::          |..:..|:.:..:|     |.|.
Human    77 --SRIRAALNAVRLLVVDPETDEQLQKLGVQVREELLRAQEAPGQAEPPAAAEVQGAGNENEPRE 139

  Fly   193 ASRDISVVLHVAPRTKLGLGIC---KGP----------EWKPGIFVQFTKDRSVAREAGLRPGDQ 244
            |.:.......:.||      :|   |||          :.|||.|::.....|.|..:|||..|:
Human   140 ADKSHPEQRELRPR------LCTMKKGPSGYGFNLHSDKSKPGQFIRSVDPDSPAEASGLRAQDR 198

  Fly   245 ILSVNSIDFSDVLFSEAVAVMKS---SSKLDMVVRTA----AGCDLFP---------------GE 287
            |:.||.:........:.|:.:::   .:||.:|.|..    ..|.:.|               ||
Human   199 IVEVNGVCMEGKQHGDVVSAIRAGGDETKLLVVDRETDEFFKKCRVIPSQEHLNGPLPVPFTNGE 263

  Fly   288 SSGYNS------------------SASSVTGDQ-----SPCWADAKSKRLTA 316
            ....||                  ||||.|.::     ||...|:.:...|:
Human   264 IQKENSREALAEAALESPRPALVRSASSDTSEELNSQDSPPKQDSTAPSSTS 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5921	NP_727061.2	PDZ_signaling	82..152	CDD:238492	20/71 (28%)
		PDZ_signaling	197..276	CDD:238492	23/94 (24%)
SLC9A3R1	NP_004243.1	PDZ_signaling	12..91	CDD:238492	23/80 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	114..192		18/83 (22%)
		PDZ_signaling	152..231	CDD:238492	22/84 (26%)
		EBP50_C	235..358	CDD:312529	15/81 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	277..358		9/39 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810