DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5921 and Slc9a3r2

DIOPT Version :9

Sequence 1:	NP_727061.2	Gene:	CG5921 / 31538	FlyBaseID:	FBgn0029835	Length:	886	Species:	Drosophila melanogaster
Sequence 2:	NP_075542.2	Gene:	Slc9a3r2 / 65962	MGIID:	1890662	Length:	337	Species:	Mus musculus

Alignment Length:	324	Identity:	74/324 - (22%)
Similarity:	123/324 - (37%)	Gaps:	84/324 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 LRVLRLVRPHQRRLLVGGPERGSTYGFTVRG--GREHGTGFFVSHVEHGGEAHLKGLRIGDQILR 123
            :..|..:||...||:.|  |:|  |||.:.|  ||.   |.|:..||.|..|....||.||:::.
Mouse     1 MAALESLRPRLCRLVRG--EQG--YGFHLHGEKGRR---GQFIRRVEPGSPAEAAALRAGDRLVE 58

  Fly   124 INGFRLDDAVHKEFIQ---LVAGQDRV------------------TLKVRGVGMLPVRDLPEERL 167
            :||..::...|.:.:|   .|.||.::                  |.::...|:.|..:..|.:.
Mouse    59 VNGVNVEGETHHQVVQRIKAVEGQTQLLVVDKETDEELCRRQLTCTEEMAHRGLPPAHNPWEPKP 123

  Fly   168 SWSVVKLPSVSGTPSESSFKGERRGASRDISVVLHVAPRTKLGLGIC---KGPEW---------- 219
            .|      :.||:....:.:.:..|..|::      .||      :|   :||:.
Mouse   124 DW------ACSGSLGSDTGQKDVNGPPREL------RPR------LCHLRRGPQGYGFNLHSDKS 170

  Fly   220 KPGIFVQFTKDRSVAREAGLRPGDQILSVNSIDFSDVLFSEAVAVMKSSSKLDMVVRTAAGCD-- 282
            :||.:::.....|.|..:|||..|:::.||..:...:..:|.||.:|:......::......|
Mouse   171 RPGQYIRSVDPGSPASHSGLRAQDRLIEVNGQNVEGLRHAEVVARIKAQEDEARLLVVDPETDEH 235

  Fly   283 -----LFPGESSGYNSSASSVTGDQSPCWADAKSKRLTAVREESGAGGGGC-GLSSAPGAGSPN 340
                 :.|.|........|.||...||...:               ||..| ..|..||:...|
Mouse   236 FKRLRVIPTEEHVEGPLPSPVTNGTSPAQLN---------------GGSVCSSRSDLPGSEKDN 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5921	NP_727061.2	PDZ_signaling	82..152	CDD:238492	25/92 (27%)
CG5921	NP_727061.2	PDZ_signaling	197..276	CDD:238492	19/91 (21%)
Slc9a3r2	NP_075542.2	PDZ_signaling	9..88	CDD:238492	29/85 (34%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	112..147		7/40 (18%)
		PDZ	148..230	CDD:214570	19/87 (22%)
		EBP50_C	232..337	CDD:286142	15/68 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	242..337		14/58 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810