Protein Alignment CG5921 and Pdzk1

DIOPT Version :9

• Sequence 1: NP_727061.2
• Gene: CG5921 / 31538
• FlyBaseID: FBgn0029835
• Length: 886
• Species: Drosophila melanogaster
• Sequence 2: NP_001139473.1
• Gene: Pdzk1 / 59020
• MGIID: 1928901
• Length: 519
• Species: Mus musculus
• Alignment Length: 617
• Identity: 132/617 - (21%)
• Similarity: 212/617 - (34%)
• Gaps: 174/617 - (28%)

  Fly    80 ERGSTYGFTVRGGREHGTGFFVSHVEHGGEAHLKGLRIGDQILRINGFRLDDAVHKEFIQLV--A 142
            :.|..|||.:|..:: ..|..:..:|.|..|...||..||::|||||..:|...|.:.::||  :
Mouse    15 QEGQNYGFFLRIEKD-TDGHLIRVIEEGSPAEKAGLLDGDRVLRINGVFVDKEEHAQVVELVRKS 78

  Fly   143 GQDRVTLKVRGVGMLPVRDLPEERLSWSVVKLPSVSGTPSESSFKGERRGASRDISVVLHVAPR- 206
            |.....|.:.|       |..|:.:. :.|.|..:..:..|::...::.|...:.:|.....||
Mouse    79 GNSVTLLVLDG-------DSYEKAVK-NQVDLKELDQSQREAALNDKKPGPGMNGAVEPCAQPRL 135

  Fly   207 -------TKLGLGICKGPEWKPGIFVQFTKDRSVAREAGLRPGDQILSVNSIDFSDVLFSEAV-A 263
                   ...|..: |..:.|.|:::.....:.||.:||:...|.::.||..:..:....|.| .
Mouse   136 CYLVKEGNSFGFSL-KTIQGKKGVYLTNIMPQGVAMKAGVLADDHLIEVNGENVENASHEEVVEK 199

  Fly   264 VMKSSSKLDMVVRTAAGCDLFPGESSGYNSSASSVTGDQSPCWADAKS--KRLTA---------- 316
            |.||.|::..::                      |..:.:.|.::.|:  ||.||
Mouse   200 VTKSGSRIMFLL----------------------VDKETARCHSEQKTQFKRETASLKLLPHQPR 242

  Fly   317 -VREESGAGGGGCGLSSAPGAGSPNWSQGVEVHKQMNKTIIKLTENGTSI------NNTYIASTG 374
             |..:.|:.|.|..|.:.|               :....|||..|.|:..      ||..:.:..
Mouse   243 VVVIKKGSNGYGFYLRAGP---------------EQKGQIIKDIEPGSPAEAAGLKNNDLVVAVN 292

  Fly   375 GSSVSGSGSTGSGTSGRSQQSQSNPSNPSRNSTTMKRSHLRPVNSAGSGIGLSSGSAGSAGSAGS 439
            |.||......|.....|....|          ||:    |.....|.|...|:..|......:..
Mouse   293 GKSVEALDHDGVVEMIRKGGDQ----------TTL----LVLDKEAESIYSLARFSPLLYCQSQE 343

  Fly   440 SGSGSRSGGVIAPAPAPPPPAMNEGANASGSVGSSLSSAITEELKKRKEKQQQQQHQQRHNRDRD 504
            ..:||...|   |||.|.|      ..|:|       |..||:.:..|.|
Mouse   344 LPNGSVKEG---PAPIPAP------LEATG-------SEPTEDAEGHKPK--------------- 377

  Fly   505 RDGNGNVDRQLTGHNGNGGHRSSV-GQVSHRQRANVAGVAATLQGSERISNLTGGGGAGGAGGSN 568
                  :.|.|...:..|.|.::: ||                .|| .:..:..||.|..||..|
Mouse   378 ------LCRLLKEDDSYGFHLNAIRGQ----------------PGS-FVKEVQQGGPADKAGLEN 419

  Fly   569 GAAGAGGDQHTALMDEFKRAHQRMFRNGFHESEHKLSSLGKSSLADRSLYGREMSLLRVKNGGSG 633
            .......:......:.:.|..:|:..:|.|.:   |...||.:          .|..:.|.
Mouse   420 EDVIIEVNGENVQEEPYDRVVERIKSSGKHVT---LLVCGKMA----------YSYFQAKK---- 467

  Fly   634 GGEGSGVMPTMRPVSMGRPLVTMSTYQERGET 665
                   :|.:.  ||..|||  :...|:|||
Mouse   468 -------IPIVS--SMAEPLV--AGPDEKGET 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5921	NP_727061.2	PDZ_signaling	82..152	CDD:238492	24/71 (34%)
		PDZ_signaling	197..276	CDD:238492	20/87 (23%)
Pdzk1	NP_001139473.1	PDZ_signaling	7..87	CDD:238492	24/72 (33%)
		PDZ	132..212	CDD:214570	19/102 (19%)
		PDZ_signaling	242..320	CDD:238492	22/106 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	348..374		12/41 (29%)
		PDZ_signaling	376..455	CDD:238492	20/119 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	479..519		5/12 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810