DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5921 and pdzd3b

DIOPT Version :9

Sequence 1:	NP_727061.2	Gene:	CG5921 / 31538	FlyBaseID:	FBgn0029835	Length:	886	Species:	Drosophila melanogaster
Sequence 2:	NP_001124259.1	Gene:	pdzd3b / 566852	ZFINID:	ZDB-GENE-081022-151	Length:	524	Species:	Danio rerio

Alignment Length:	298	Identity:	80/298 - (26%)
Similarity:	124/298 - (41%)	Gaps:	50/298 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 SASLTNSAST----DCSSSMQGSTTSSASSDVMTLTTTAASSWCAIPASSRLRVLRLVRPHQRRL 74
            ::.||:||.:    .|||.|   |.....||  |..:.|......:||.:....:. .|| ||..
Zfish   203 ASELTHSAISKMVKKCSSHM---TVLVIDSD--TEKSYARRKMPILPAMADAENMP-YRP-QRLH 260

  Fly    75 LVGGPERGSTYGFTVRGGREHG----TGFFVSHVEHGGEAHLKGLRIGDQILRINGFRLDDAVHK 135
            ||.||:   .|||.:|  :|.|    |...|..|:.|..|.|.|::.|:.:|.:||...|...||
Zfish   261 LVMGPD---GYGFLLR--QEKGGAGRTVHMVREVDKGSPAELGGVKEGEMLLEVNGESTDPLSHK 320

  Fly   136 EFIQLV--AGQDRVTLKV---RG------VGMLPV-------RDLPEERLSWSVVKLPSVSGT-P 181
            :.:..:  :|| :|||..   :|      :|:.|:       ..|||.:....|...|:|... |
Zfish   321 DVVSNIRQSGQ-QVTLTTMTPQGYDFYTKLGLSPLLFCVDVPSALPEVKKEIPVTPKPAVPPVEP 384

  Fly   182 SESSFKGERRGASRDISVVLHVAPRTKLGLGICKG-PEWKPGIFVQFTKDRSVAREAGLRPGDQI 245
            .|.        ...:.:|...:..|:..|.|...| .:.|||.|:......|..:.:||..||.:
Zfish   385 QEE--------VQINPNVRRCILERSSAGFGFHLGCVQQKPGTFISQVAAGSPGQSSGLFQGDVV 441

  Fly   246 LSVNSIDFSDVLFSEAVA-VMKSSSKLDMVVRTAAGCD 282
            :.||..:.......:.:. |.:....|.::|....|.|
Zfish   442 VEVNGQNVEKESLEDVIMHVKRGGETLSLLVVDQKGYD 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5921	NP_727061.2	PDZ_signaling	82..152	CDD:238492	25/78 (32%)
CG5921	NP_727061.2	PDZ_signaling	197..276	CDD:238492	18/80 (23%)
pdzd3b	NP_001124259.1	PDZ_signaling	44..118	CDD:238492
		PDZ	148..227	CDD:214570	9/26 (35%)
		PDZ_signaling	264..336	CDD:238492	26/77 (34%)
		PDZ	393..473	CDD:214570	18/79 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810