DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5921 and lnx2b

DIOPT Version :9

Sequence 1:	NP_727061.2	Gene:	CG5921 / 31538	FlyBaseID:	FBgn0029835	Length:	886	Species:	Drosophila melanogaster
Sequence 2:	NP_998105.2	Gene:	lnx2b / 564464	ZFINID:	ZDB-GENE-040426-2500	Length:	678	Species:	Danio rerio

Alignment Length:	262	Identity:	66/262 - (25%)
Similarity:	107/262 - (40%)	Gaps:	57/262 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 ERGSTYGF-TVRGGREHGTGFFVSHVEHGGEAHLKG-LRIGDQILRINGFRLDDAVHKEFIQLVA 142
            ||....|. .:|...|  .|.|:..:..||.|...| ||..|::|.|||..|.....:...|::.
Zfish   334 ERSEALGIKLIRKSEE--PGVFILDLLPGGLAAKDGKLRNNDKVLGINGQDLRHGTPESAAQIIQ 396

  Fly   143 GQDRVTLKVRGVGMLPVRDLPEERLSWSVVKLPSVSGTPSESSFKGERR---------------- 191
            ..                   |.|:::.|::|..||....|...:|.||
Zfish   397 AS-------------------EMRVNFVVMRLQDVSEEGGEGQSRGARRVPEPQYFRRHSEYMKE 442

  Fly   192 ----GASRDISVVLHVAPRTKLGLGICKGPEWKPGIFVQFTKDRSVA---REAGLRPGDQILSVN 249
                .:|::.:|.|...||..||:.|..|.:.:..:.|..|..:.|.   |:..::.||.:||:|
Zfish   443 PPGGFSSQEKTVTLKKEPRQSLGITIAGGRDCRSRLPVYITSVQPVGCLHRDGTVKTGDVLLSIN 507

  Fly   250 SIDFSDVLFSEAVAVMKS----SSKLDMVVRTAAGCDLFPGESSGYNSSASSVTGDQS------P 304
            .||.:.:.::|||.|:|:    |:....|::|.|..:...|| ||......::.|.:.      |
Zfish   508 GIDLTHLTYNEAVTVLKTQTAQSTVTLRVIQTFADDEEQDGE-SGSREDMDTMEGPKDDDINWVP 571

  Fly   305 CW 306
            .|
Zfish   572 LW 573

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5921	NP_727061.2	PDZ_signaling	82..152	CDD:238492	18/71 (25%)
CG5921	NP_727061.2	PDZ_signaling	197..276	CDD:238492	26/85 (31%)
lnx2b	NP_998105.2	RING	46..82	CDD:214546
		PDZ_signaling	210..291	CDD:238492
		PDZ_signaling	325..406	CDD:238492	22/92 (24%)
		PDZ_signaling	451..537	CDD:238492	25/85 (29%)
		PDZ_signaling	587..671	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900