Protein Alignment CG5921 and ush1c

DIOPT Version :10

• Sequence 1: NP_727061.2
• Gene: CG5921 / 31538
• FlyBaseID: FBgn0029835
• Length: 886
• Species: Drosophila melanogaster
• Sequence 2: NP_001429364.1
• Gene: ush1c / 564412
• ZFINID: ZDB-GENE-060312-41
• Length: 983
• Species: Danio rerio
• Alignment Length: 792
• Identity: 176/792 - (22%)
• Similarity: 275/792 - (34%)
• Gaps: 268/792 - (33%)

  Fly    58 SSRLRVLRLVRPHQRRLLVGGPERGSTYGFTVRGGREHGTGFFVSHVEHGGEAHLKGLRIGDQIL 122
            |.:|:.:||.|.|...|           |.:||||.|.|:|.|:|.:...|:|...||::||:|:
Zfish    92 SRKLKEVRLDRTHPEGL-----------GLSVRGGLEFGSGLFISQIVKDGQAGNVGLQVGDEIV 145

  Fly   123 RINGFRLDDAVHKEFIQLVAGQDRVTLKVRGVGMLPVRDLPEERLSWSVV-KLPSVSGTPSES-- 184
            ||||:.:...:|:|.|.|:..:..|:||||.|||:||:...:|.|.|..| :..|.||..|.|
Zfish   146 RINGYSISSCIHEEVINLIKTKKTVSLKVRHVGMIPVKSSSDEPLKWQFVDQFVSESGEKSNSIA 210

  Fly   185 ---SFKGERRGASRDISVVLHVAPRTKLGLGICKGPEWKPGIFVQFTKDRSVAREAGLRPGDQIL 246
               |..|..   .::..|.|.:.....:|:.|..||..||||:|...|..|::.|.||:.||||:
Zfish   211 GLASIGGNE---IKEKKVFLSLVGTKGMGISISSGPTKKPGIYVSNVKPGSLSAEVGLQVGDQIV 272

  Fly   247 SVNSIDFSDVLFSEAVAVMKSSSKLDMVVRTAAGCDLFPGESSGYNSSASSVTGDQSPCWADAKS 311
            .||.::|:::...|||.|:|||..|.:.|.|.||.:||              ..|:.....:|:.
Zfish   273 EVNGVEFTNLSHQEAVRVLKSSRSLTITVLTGAGSELF--------------MTDEERLAVEARH 323

  Fly   312 K--RLTAVREESGAGGGGCGLSSAPGAGSPNWSQGVEVHKQMNKTIIKLTENGTSINNTYIASTG 374
            :  |...:.::..|                     :|.:|.:.:...|..:....|:..
Zfish   324 ELDRQELMHQKKVA---------------------LETNKIVKEQQEKERQRKMEISQK------ 361

  Fly   375 GSSVSGSGSTGSGTSGRSQQSQSNPSNPSRNSTTMKRSHLRPVNSAGSGIGLSSGSAGSAGSAGS 439
                            .:::.:.......|.....|:.|....:..||.....|.|.
Zfish   362 ----------------AAEEEERYRKEMERIEAAEKKHHKEWEDDWGSKEKKKSVSP-------- 402

  Fly   440 SGSGSRSGGVIAPAPAPPPPA-----------------MNEG---------ANASGSVGSSLSSA 478
                       |.:|:||||.                 ..||         .........|.:..
Zfish   403 -----------AASPSPPPPTRLAPSPKPKTSTFGWFYRYEGKLPTLKKKEKETKKKKKMSKTDT 456

  Fly   479 ITEELKKRKEKQQQQQHQQRHNRDRDRDGNGNVDRQLTGHNGNGGHRSSVGQVSHRQRANVAGVA 543
            :..|.|.:||.:.:.:..:......:|:....:.|.|.             :||..:|.:
Zfish   457 LPTEKKSKKEMEFELKLAKEKEEILEREKQMKISRLLQ-------------EVSETERED----- 503

  Fly   544 ATLQGSERISNLTGGGGAGGAGGSNGAAGAGGDQHTALMDEFKRAHQRMFRNGFHESEHKLSSLG 608
              |:.||::                        ||..         :|:.:....:    :||:.
Zfish   504 --LEESEKV------------------------QHWV---------ERLCQTRLEQ----ISSVE 529

  Fly   609 KSSLADRSLYGREMSLLRVKNGGSGGGEGSGVMPTMRPVSMGRPLVTM--------STYQERGET 665
            ..|        .|||..|     |....|    ||.|....|..|.|.        ...|...:.
Zfish   530 NES--------PEMSPTR-----SPASTG----PTRRRFPGGLTLATTDLDDINLDDVDQSLRQP 577

  Fly   666 LKRTSIMPDESCYRNSINSNNNNGFSRNRS--------------NSNTNNNNRLQSQNGVNPANG 716
            |||.:..|..|                |:.              :|||   :|.||....:|...
Zfish   578 LKRLAPTPPTS----------------NQPPPPLPLPPPSPRLYHSNT---HRPQSPRSQHPMQS 623

  Fly   717 NGSPELPPPPPQFANPQPKQMPPQHIKPMTGNAAANGSGSANGLGNGSLAKVRQPMSPMRSASIS 781
            ..:|:.||.||      ..::||                       .|:.:.|.|.|....:|..
Zfish   624 RPAPQRPPSPP------ASRVPP-----------------------SSIGRSRPPPSAPLFSSRG 659

  Fly   782 VGGFRPPATPQP 793
            :..|:||..|.|
Zfish   660 LSSFQPPPPPPP 671

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5921	NP_727061.2	PDZ1_harmonin	72..155	CDD:467219	31/82 (38%)
		PDZ_canonical	195..276	CDD:483948	31/80 (39%)
ush1c	NP_001429364.1	None