DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5921 and Tamalin

DIOPT Version :9

Sequence 1:	NP_727061.2	Gene:	CG5921 / 31538	FlyBaseID:	FBgn0029835	Length:	886	Species:	Drosophila melanogaster
Sequence 2:	NP_062391.3	Gene:	Tamalin / 56149	MGIID:	1860303	Length:	392	Species:	Mus musculus

Alignment Length:	335	Identity:	69/335 - (20%)
Similarity:	105/335 - (31%)	Gaps:	136/335 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 QRRLLVGGPERGSTYGFTVRG-GREHGTG------FFVSHVEHGGEAHLKGLRIGDQILRINGFR 128
            ||::|........|:||.::. |..|...      .||..|.....|.|.||..||.|..:||..
Mouse    97 QRKVLTLEKGDNQTFGFEIQTYGLHHREEQRVEMVTFVCRVHESSPAQLAGLTPGDTIASVNGLN 161

  Fly   129 LDDAVHKEFIQLVAGQDRVTLKVRGVGMLPVRDLPEERLSWSVVKLPSVSGTP------------ 181
            ::...|:|.:.::                        :.|.:|::|.::.||.
Mouse   162 VEGIRHREIVDII------------------------KASGNVLRLETLYGTSIRKAELEARLQY 202

  Fly   182 -SESSFKGERRGASRDISV----VLHVAPRTKLGLGICKGPEWKPGIFVQFTKDRSVAREAGLRP 241
             .::.:  |:.|..|.:.|    ::|       || :.|    .|.|:......||....|||.|
Mouse   203 LKQTLY--EKWGEYRSLMVQEQRLVH-------GL-VVK----DPSIYDTLESVRSCLYGAGLLP 253

  Fly   242 GDQILSVNSIDFSDVLFSEAVAVMKSSSKLDMVVRTAAGCDLFPGESSGYNSSASSVTGD----- 301
            |       |:.|..:|.:                         ||.:.|....|...|.|
Mouse   254 G-------SLPFGPLLAA-------------------------PGSARGGARRAKGDTDDAVYHT 286

  Fly   302 --------------------------QSPCWADAKSKRLTAVREES----GAGGGGCGLSSAPGA 336
                                      ::|......:.|.|..|..|    |.||||    .||||
Mouse   287 CFFGGAEPQALPPPPPPARALGPSSAETPASVLFPAPRSTLSRSASVRCAGPGGGG----GAPGA 347

  Fly   337 GSPNWSQGVE 346
               .|::..|
Mouse   348 ---LWTEARE 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5921	NP_727061.2	PDZ_signaling	82..152	CDD:238492	19/76 (25%)
CG5921	NP_727061.2	PDZ_signaling	197..276	CDD:238492	17/82 (21%)
Tamalin	NP_062391.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..50
		PDZ_signaling	99..184	CDD:238492	22/108 (20%)
		Interaction with PSCD3. /evidence=ECO:0000269\|PubMed:10828067	180..257		22/97 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	294..315		0/20 (0%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900