DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5921 and lnx1

DIOPT Version :9

Sequence 1:	NP_727061.2	Gene:	CG5921 / 31538	FlyBaseID:	FBgn0029835	Length:	886	Species:	Drosophila melanogaster
Sequence 2:	XP_005160562.1	Gene:	lnx1 / 561226	ZFINID:	ZDB-GENE-030131-9439	Length:	769	Species:	Danio rerio

Alignment Length:	289	Identity:	78/289 - (26%)
Similarity:	116/289 - (40%)	Gaps:	46/289 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 VRGGREHGTGFFVSHVEHGGEAHLKG-LRIGDQILRINGFRLDDAVHKEFIQLV-AGQDRVTLKV 151
            ||...|||.  |:.|:..||.|...| ||:.|::|.|||..|.....:....|: |.:|||...|
Zfish   429 VRRPDEHGV--FIFHLLEGGLAARDGRLRVDDRVLAINGHDLRYGAPEHAALLIQASEDRVHFIV 491

  Fly   152 RGVGMLPVRDLPEERLSWSVVKLPSVSGTPSESSFKGE-RRGASRDISVVLHVAPRTKLGLGICK 215
            .....:|..|:.:| ..|::...|..|....|.:.... ::.|..:.:|.|...|...||:.:..
Zfish   492 SRQTHIPAPDILQE-APWNMEGPPPYSPVDIEHTLLDSCQKPACYEKTVTLLKEPHDSLGMTVAG 555

  Fly   216 GPE---WKPGIFV-QFTKDRSVAREAGLRPGDQILSVNSIDFSDVLFSEAVAVMKSSSK------ 270
            |..   |...::| ....:..|.:|..:|.||.:|:||.:|.:.|..|||||.:|::|.
Zfish   556 GMSSRGWDLPVYVTNVDPNGVVGQEGSIRKGDILLNVNGVDLTGVTRSEAVANLKNTSSPVVLQV 620

  Fly   271 LDMVVRTAAGCDLFPGESSGYNSSASS--------VTGDQSPCWA-------------DAKSKRL 314
            |:|.....:..|..|...|....|.||        ...|.:|.|.             |...:|.
Zfish   621 LEMRPPNESSLDCMPPLHSPCALSPSSPGDVKLPPPNDDYAPLWVSWLQLPRHLYCCKDIVLRRS 685

  Fly   315 TAVREESGAGGGGCGLSSAPGAGSPNWSQ 343
            |:         |..|.|...|....|.:|
Zfish   686 TS---------GSLGFSIVGGQEELNCNQ 705

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5921	NP_727061.2	PDZ_signaling	82..152	CDD:238492	24/64 (38%)
CG5921	NP_727061.2	PDZ_signaling	197..276	CDD:238492	27/88 (31%)
lnx1	XP_005160562.1	RING	57..93	CDD:214546
		PDZ_signaling	297..381	CDD:238492
		PDZ_signaling	411..491	CDD:238492	24/63 (38%)
		PDZ_signaling	536..621	CDD:238492	25/84 (30%)
		DegQ	<548..621	CDD:223343	22/72 (31%)
		PDZ_signaling	678..762	CDD:238492	9/37 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900