DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5921 and lnx2a

DIOPT Version :9

Sequence 1:	NP_727061.2	Gene:	CG5921 / 31538	FlyBaseID:	FBgn0029835	Length:	886	Species:	Drosophila melanogaster
Sequence 2:	NP_001106696.2	Gene:	lnx2a / 553331	ZFINID:	ZDB-GENE-060228-2	Length:	737	Species:	Danio rerio

Alignment Length:	321	Identity:	80/321 - (24%)
Similarity:	121/321 - (37%)	Gaps:	84/321 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 CSSSMQGSTTSSASSDVMTLTTTAASSWCAIPASSRLRVLRLVRPHQRRLLVGGPERGSTYGF-T 88
            ||:....:|.|...|                |||.|:.:      |:|       |.....|. .
Zfish   357 CSARPPAATASPKGS----------------PASIRITL------HKR-------ESSEQLGIKL 392

  Fly    89 VRGGREHGTGFFVSHVEHGGEAHLKG-LRIGDQILRINGFRLDDAVHKEFIQLV-AGQDRVTLKV 151
            ||  |....|.|:..:..||.|...| |...|::|.:|...|.....:...|:: |..:||.|.:
Zfish   393 VR--RTDEAGVFILDLLEGGLAAKDGRLCSNDRVLAVNEHDLRHGTPELAAQIIQASGERVNLLI 455

  Fly   152 R---------GVGMLPVRDLPEERLSWS---VVKLPSVSGTPSE-SSFKGERRGASRDIS----- 198
            .         ..|....||:      ||   :..||| :.|||. .|....|....||:|
Zfish   456 SRSSKQTMAVHTGSTLTRDI------WSHDHIPPLPS-TATPSPVPSLHLARSSTQRDLSQCVNC 513

  Fly   199 ----VVLHVAPRTKLGLGICKGPEWKPG---IFVQFTKDRS-VAREAGLRPGDQILSVNSIDFSD 255
                :.:...|...||:.:..|...|.|   |||...:... ::|:..::.||.:||:|..|.:.
Zfish   514 KEKHITVKKEPHESLGMTVAGGRGSKSGELPIFVTSVQPHGCLSRDGRIKRGDVLLSINGQDLTY 578

  Fly   256 VLFSEAVAVMKSSS----------KLDMVVRTAAGCDLFPGESSGYNSSASSVTGDQSPCW 306
            :..||||..:|||:          ::.||.......:|.|...:.|::|       .||.|
Zfish   579 LSHSEAVGTLKSSATSCSVQLKALEVTMVEEPGLDEELLPPHENDYDAS-------WSPSW 632

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5921	NP_727061.2	PDZ_signaling	82..152	CDD:238492	20/72 (28%)
CG5921	NP_727061.2	PDZ_signaling	197..276	CDD:238492	26/101 (26%)
lnx2a	NP_001106696.2	zf-RING_2	49..87	CDD:290367
		PDZ	267..353	CDD:214570
		PDZ_signaling	375..455	CDD:238492	24/94 (26%)
		PDZ_signaling	515..600	CDD:238492	23/84 (27%)
		PDZ_signaling	646..730	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900