Protein Alignment CG5921 and PDZK1

DIOPT Version :9

• Sequence 1: NP_727061.2
• Gene: CG5921 / 31538
• FlyBaseID: FBgn0029835
• Length: 886
• Species: Drosophila melanogaster
• Sequence 2: XP_024303384.1
• Gene: PDZK1 / 5174
• HGNCID: 8821
• Length: 539
• Species: Homo sapiens
• Alignment Length: 572
• Identity: 118/572 - (20%)
• Similarity: 185/572 - (32%)
• Gaps: 188/572 - (32%)

  Fly    37 ASSDVMTLTTTAASSWCAIPASSRLRVLRLVRPHQRRLLVGGPERGSTYGFTVRGGREHGTGFFV 101
            :|..|:.|||...|::               .|.:.:|   ..:.|..|||.:|..:: ..|..|
Human    10 SSPKVLVLTTEMTSTF---------------NPRECKL---SKQEGQNYGFFLRIEKD-TEGHLV 55

  Fly   102 SHVEHGGEAHLKGLRIGDQILRINGFRLDDAVHKEFIQLVAGQDRVTLKVRGVGMLPVRDLPEER 166
            ..||....|...||:.||::|||||..:|...|.:.:.||                        |
Human    56 RVVEKCSPAEKAGLQDGDRVLRINGVFVDKEEHMQVVDLV------------------------R 96

  Fly   167 LSWSVVKLPSVSGTPSESSFK-----------GERRGASRDI-SVVLHVAPRTKLGLGIC----- 214
            .|.:.|.|..:.|...|.:.|           .:.:|.|.:| |.|::...:|.....:|
Human    97 KSGNSVTLLVLDGDSYEKAVKTRVDLKELGQSQKEQGLSDNILSPVMNGGVQTWTQPRLCYLVKE 161

  Fly   215 --------KGPEWKPGIFVQFTKDRSVAREAGLRPGDQILSVNSIDFSDVLFSEAVAVMKSSSKL 271
                    |..:.|.|:::.....:.||..||:...|.::.||..:..|....|.|..:|.|...
Human   162 GGSYGFSLKTVQGKKGVYMTDITPQGVAMRAGVLADDHLIEVNGENVEDASHEEVVEKVKKSGSR 226

  Fly   272 DMVVRTAAGCDLFPGESSGYNSSASSVTGDQSPCWADAKSKRLTA-----------VREESGAGG 325
            .|.:       |...|:            |:.......:.||.||           |..:.|:.|
Human   227 VMFL-------LVDKET------------DKRHVEQKIQFKRETASLKLLPHQPRIVEMKKGSNG 272

  Fly   326 GGCGLSSAPGAGSPNWSQGVEVHKQMNKTIIKLTENGTSI------NNTYIASTGGSSVSGSGST 384
            .|..|.    |||....|           |||..::|:..      ||..:.:..|.||......
Human   273 YGFYLR----AGSEQKGQ-----------IIKDIDSGSPAEEAGLKNNDLVVAVNGESVETLDHD 322

  Fly   385 GSGTSGRSQQSQSNPSNPSRNSTTMKR-SHLRPVNSAGSGIGLSSGSAGSAGSAGSSGSGSRSGG 448
            ......|....|::.....:.:..|.| :|..|.....|. .|.:||
Human   323 SVVEMIRKGGDQTSLLVVDKETDNMYRLAHFSPFLYYQSQ-ELPNGS------------------ 368

  Fly   449 VIAPAPAPPPPAMNEGANASGSVGSSLSSAITEELKKRKEKQQQQQHQQRHNRDRDRDGNGNVDR 513
             :..||||.|.::                    |:....:..::..|:.:            :.|
Human   369 -VKEAPAPTPTSL--------------------EVSSPPDTTEEVDHKPK------------LCR 400

  Fly   514 QLTGHNGNGGHRSSVGQVSHRQRANVAGVAATLQGSERISNLTGGGGAGGAG 565
            ...|.||.|.|.:::               ..|.|| .|..:..||.|..||
Human   401 LAKGENGYGFHLNAI---------------RGLPGS-FIKEVQKGGPADLAG 436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5921	NP_727061.2	PDZ_signaling	82..152	CDD:238492	23/69 (33%)
		PDZ_signaling	197..276	CDD:238492	21/92 (23%)
PDZK1	XP_024303384.1	PDZ_signaling	27..107	CDD:238492	29/107 (27%)
		PDZ	152..232	CDD:214570	17/86 (20%)
		PDZ_signaling	261..340	CDD:238492	20/93 (22%)
		PDZ	395..475	CDD:214570	15/70 (21%)
		F1-ATPase_gamma	<457..>501	CDD:320933

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810