DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5921 and PDZD11

DIOPT Version :9

Sequence 1:	NP_727061.2	Gene:	CG5921 / 31538	FlyBaseID:	FBgn0029835	Length:	886	Species:	Drosophila melanogaster
Sequence 2:	XP_016885057.1	Gene:	PDZD11 / 51248	HGNCID:	28034	Length:	172	Species:	Homo sapiens

Alignment Length:	148	Identity:	46/148 - (31%)
Similarity:	69/148 - (46%)	Gaps:	28/148 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   160 RDLPE--ERL---SWSVVKLPSVSGTPS---------ESSFKGE-RRGASRDISVVLHVAPRTKL 209
            |.|||  .|:   .:.||.||:....|:         ...:..| .:...|  ::.|...|..:|
Human    28 RALPEMDSRIPYDDYPVVFLPAYENPPAWIPPHERVHHPDYNNELTQFLPR--TITLKKPPGAQL 90

  Fly   210 GLGICKGPEWKPGIFVQFTKDRSVAREAGLRPGDQILSVNSIDFSDVLFSEAVAVMKSSSKLDMV 274
            |..|..|...:.|||:......|.|..|||:.|||:|:||.:||.|:..|:||.::|::.::.|.
Human    91 GFNIRGGKASQLGIFISKVIPDSDAHRAGLQEGDQVLAVNDVDFQDIEHSKAVEILKTAREISMR 155

  Fly   275 VRTAAGCDLFPGESSGYN 292
            ||      .||     ||
Human   156 VR------FFP-----YN 162

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5921	NP_727061.2	PDZ_signaling	82..152	CDD:238492
CG5921	NP_727061.2	PDZ_signaling	197..276	CDD:238492	28/78 (36%)
PDZD11	XP_016885057.1	PDZ_signaling	77..157	CDD:238492	29/81 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810