Protein Alignment CG5921 and LOC4577298

DIOPT Version :10

• Sequence 1: NP_727061.2
• Gene: CG5921 / 31538
• FlyBaseID: FBgn0029835
• Length: 886
• Species: Drosophila melanogaster
• Sequence 2: XP_001231159.4
• Gene: LOC4577298 / 4577298
• VectorBaseID: AGAMI1_006307
• Length: 722
• Species: Anopheles gambiae
• Alignment Length: 858
• Identity: 284/858 - (33%)
• Similarity: 389/858 - (45%)
• Gaps: 229/858 - (26%)

  Fly     5 TAASASISTSASLTNSASTDCSSSMQGSTTSSASSDVMTLTTTAASSWCAIPASSRLRVLRLVRP 69
            |:|:.||:|.|:...      |.|..|:...|     :.|..:...........:|:|.:|||||
Mosquito    11 TSAATSIATPATFRP------SKSRHGAREKS-----LPLHKSLGEGAMDAGQQARVRTVRLVRP 64

  Fly    70 H----QRRLLVGGPERGSTYGFTVRGGREHGTGFFVSHVEHGGEAHLKGLRIGDQILRINGFRLD 130
            |    .|.|    |..||.:||::|||.|:|||||||.:|...||..:||::||||:|:||::::
Mosquito    65 HHGYSHRNL----PITGSNFGFSIRGGLEYGTGFFVSAIERDSEADRQGLKVGDQIIRVNGYQVE 125

  Fly   131 DAVHKEFIQLVAGQDRVTLKVRGVGMLPVRDLPEERLSWSVVKLPSVSGTPSESSFKGERRGASR 195
            ||||:|..|.:|.|:|:.:||||:|:||:::...:.|:|.||.. .:|....::....|..| .|
Mosquito   126 DAVHRELAQFIANQERLIMKVRGLGILPIKERTADPLTWHVVSF-GMSRDKQDALLLEEPCG-GR 188

  Fly   196 DISVVLHVAPRTKLGLGICKGPEWKPGIFVQFTKDRSVAREAGLRPGDQILSVNSIDFSDVLFSE 260
            |:.|:|.||||||||.||||||:|||||||||||:..|||||||||||||||.|...|::..|.|
Mosquito   189 DVKVILSVAPRTKLGCGICKGPDWKPGIFVQFTKEGGVAREAGLRPGDQILSCNGHSFAEATFGE 253

  Fly   261 AVAVMKSSSKLDMVVRTAAGCDLFPGESSGYNSSASSVTGDQSPCWADAKSKRLTAVREESGAGG 325
            ||||||||..|::|||.:||.|||||||||||||||||.|||||||.|..||||:.||||| ...
Mosquito   254 AVAVMKSSHVLELVVRPSAGLDLFPGESSGYNSSASSVNGDQSPCWGDQTSKRLSIVREES-ITH 317

  Fly   326 GGCGLSSAPGAGSPNW------SQGV------------------EVHKQMNKTIIKLTENGTSI- 365
            ....|::||.|..|..      ..||                  :|.:|..:...:||..||..
Mosquito   318 DRRRLAAAPVATVPEMPPASDSKSGVPPPPPPQPQQQLHHQDEQQVQQQQQQQQQQLTPRGTLAG 382

  Fly   366 ------NNTYIA-STGGSSVSGSGSTGSGTSGRSQQSQSNP-SNPSRNSTTMKRSHLRPVNSAGS 422
                  |.|.|. |..|:.|                   || :..|...|.:...|
Mosquito   383 GATRRKNTTIIEFSERGAIV-------------------NPEAKQSETKTIIVEVH--------- 419

  Fly   423 GIGLSSGSAGSAGSAGSSGSGSRSGGVIAPAPAPPPP------------AMNEGANASGS----- 470
                .|.||||... ..:|.|:.:.|.|.|   ||||            ::...|.||.|
Mosquito   420 ----RSASAGSMVD-DETGHGAAAAGTIIP---PPPPLFADTVTTSSCQSVTNAAAASSSTTLAQ 476

  Fly   471 -------VGSSLSSAITEELKKRKEKQQQQQHQQRHNRDRDRDGNGNVDRQLTGHNGNGGHRSSV 528
                   ...|||:||::||::|.:|:....            |.|..|...       |..:::
Mosquito   477 EQASAAAAHHSLSNAISDELRRRAQKKAAPA------------GGGATDPAT-------GPAAAL 522

  Fly   529 GQVSHR-QRANVAGVAATLQGSERISNLTGGGGAGGAGGSNGAAGAGGDQHTALMDEFKRAHQRM 592
            .::.:| :..||.....|:..|:                         ::||||||||:..|:||
Mosquito   523 TELENRLKEKNVRLRPVTMAISD-------------------------ERHTALMDEFRAVHKRM 562

  Fly   593 FRNGFHESEHKLSSLGKSSLADRSLYGREMSLLRVKNGGSGGGEG-SGVMPTMRPVSMGRPLVTM 656
            |:|||..:|.| ....|::.||   :|:.:.  ...||.:|..:. .|.|..:....|.:
Mosquito   563 FKNGFDNAELK-KQPPKTNDAD---HGQPIQ--DAVNGANGARKSPKGTMGRVAASEMAK----- 616

  Fly   657 STYQERGETLKRTSIMPDESCYRNSINSNNNNGFSRNRSNSNTNNNNRLQSQNGVNPANGNGSPE 721
                ..|::.:..||        .|...||                                 |:
Mosquito   617 ----ASGDSAELESI--------ESFKLNN---------------------------------PQ 636

  Fly   722 LPP--PPPQFANPQ---PKQMPPQHIKPMTGNAAANGSGSANGLGNGSLAK--VRQPMSPMRSAS 779
            .||  ||..:..||   |..|.... ||:    |...|..|...|.....|  .|.....:||.:
Mosquito   637 QPPVRPPSYYFCPQATGPPTMKKSQ-KPI----AVTISEYATSAGRTEEPKKTTRFDFGQLRSVT 696

  Fly   780 ISVGGFRPPATPQ 792
            .::||..|...|:
Mosquito   697 EAIGGGGPVGGPK 709

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5921	NP_727061.2	PDZ1_harmonin	72..155	CDD:467219	43/82 (52%)
		PDZ_canonical	195..276	CDD:483948	58/80 (73%)
LOC4577298	XP_001231159.4	None