DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5921 and Lnx1

DIOPT Version :9

Sequence 1:	NP_727061.2	Gene:	CG5921 / 31538	FlyBaseID:	FBgn0029835	Length:	886	Species:	Drosophila melanogaster
Sequence 2:	NP_001101828.1	Gene:	Lnx1 / 360926	RGDID:	1308159	Length:	728	Species:	Rattus norvegicus

Alignment Length:	323	Identity:	86/323 - (26%)
Similarity:	124/323 - (38%)	Gaps:	72/323 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    98 GFFVSHVEHGGEAHLKG-LRIGDQILRINGFRL-----DDAVHKEFIQLVAGQDRVTLKVRGVGM 156
            |.|:.:|.:||.|...| |...|::|.|||..|     :.|.|  .||  |.:.||.|.|.....
  Rat   409 GVFIFNVLNGGVADRHGQLEENDRVLAINGHDLRFGSPESAAH--LIQ--ASERRVHLVVSRQVR 469

  Fly   157 LPVRDLPEERLSWSVVKLPSVSGTPSESSFKGERRGASRDISVVLHVAPRTKLGLGICKGP---E 218
            .|..|:.:|....|..:...|||..|.||   :......:..|.:...|...||:.:..|.   |
  Rat   470 QPSPDIFQEAGCISNGQQSPVSGERSTSS---KPAATCHEKVVSVQKDPNESLGMTVGGGASHRE 531

  Fly   219 WKPGIFVQFTKDRSV-AREAGLRPGDQILSVNSIDFSDVLFSEAVAVMKSSSKLDMVVR------ 276
            |...|:|...:...| :|:..::.||.:|:||.|:.::|..:||||::||:.. .:|::
  Rat   532 WDLPIYVISVEPGGVISRDGRIKTGDILLNVNGIELTEVSRTEAVAILKSTPS-SVVLKALEVKE 595

  Fly   277 --TAAGCDLFPGESSGYNSSASSVT--GDQSPCWA-------------DAKSKRLTAVREESGAG 324
              |...|      |.....|..:||  ||.||.|.             |...:|.||
  Rat   596 QETQEDC------SPAALDSNHNVTPPGDWSPSWVMWLELPQYLYNCKDVILRRNTA-------- 646

  Fly   325 GGGCGLSSAPGAGSPNWSQGVEVHKQMNKTIIKLTENGTSINN-------TYIASTGGSSVSG 380
             |..|....         .|.|.:.......||....||...|       ..:.:..|.|.||
  Rat   647 -GSLGFCIV---------GGYEEYSGNQPFFIKSIVEGTPAYNDGRIRCGDILLAVNGRSTSG 699

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5921	NP_727061.2	PDZ_signaling	82..152	CDD:238492	22/59 (37%)
CG5921	NP_727061.2	PDZ_signaling	197..276	CDD:238492	25/82 (30%)
Lnx1	NP_001101828.1	RING	45..81	CDD:214546
		DegQ	<260..364	CDD:223343
		PDZ_signaling	276..360	CDD:238492
		PDZ_signaling	384..464	CDD:238492	22/58 (38%)
		PDZ_signaling	506..589	CDD:238492	25/83 (30%)
		PDZ_signaling	637..721	CDD:238492	17/81 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900