DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5921 and Stxbp4

DIOPT Version :9

Sequence 1:	NP_727061.2	Gene:	CG5921 / 31538	FlyBaseID:	FBgn0029835	Length:	886	Species:	Drosophila melanogaster
Sequence 2:	XP_006247190.1	Gene:	Stxbp4 / 303443	RGDID:	1307903	Length:	557	Species:	Rattus norvegicus

Alignment Length:	248	Identity:	63/248 - (25%)
Similarity:	87/248 - (35%)	Gaps:	68/248 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   179 GTPS-ESSFKGERRGASRDISVVLHVAPRTKLGLGICKGPEWKPGIFV---QFTKDRSVAREAGL 239
            ||.| .||...||..|.|    |:.||..|.|||.|..|.:...|..|   :.|......::..|
  Rat     4 GTSSARSSSPLERDPAFR----VITVAKETGLGLKILGGIDRNEGPLVYIHEVTPGGDCYKDGRL 64

  Fly   240 RPGDQILSVNSIDFSDVLFSEAV-----AVMKSSSKLDMV-VRTAAGCDLFPG------------ 286
            :||||::|:|......|.|.||.     |.::..|.|::. :|..:.|. .||
  Rat    65 KPGDQLVSINKESMIGVSFEEAKNILTRAKLRWESPLEIAFIRQKSYCG-HPGNICCQSPPVSED 128

  Fly   287 ---ESSGYNSSASSVTG------DQSPCWADAKSKRLTAVR---EESGAGGGGCGLSSAPGAGSP 339
               ::|.:| ..||..|      ..:|...|:.....|.::   |.|.|     ||:..|
  Rat   129 CEPQTSAFN-LLSSPAGTLLPKTSSTPRTQDSILPSCTVIQTQPEHSQA-----GLAPVP----- 182

  Fly   340 NWSQGVEVHKQMNKTIIKLTENGTSINNTYIASTGGSSVSG-SGSTGSGTSGR 391
                             .|....|..:|..||.......|| .|......|.|
  Rat   183 -----------------SLNNRPTDTSNADIAPAWTDDASGPQGKISLNPSAR 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5921	NP_727061.2	PDZ_signaling	82..152	CDD:238492
CG5921	NP_727061.2	PDZ_signaling	197..276	CDD:238492	26/87 (30%)
Stxbp4	XP_006247190.1	PDZ_signaling	21..94	CDD:238492	24/76 (32%)
		TPR_MLP1_2	299..400	CDD:285204
		GBP_C	<306..389	CDD:303769
		coiled coil	359..369	CDD:293879
		coiled coil	378..389	CDD:293879
		WW	502..531	CDD:278809
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900