DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5921 and Tamalin

DIOPT Version :9

Sequence 1:	NP_727061.2	Gene:	CG5921 / 31538	FlyBaseID:	FBgn0029835	Length:	886	Species:	Drosophila melanogaster
Sequence 2:	NP_620249.1	Gene:	Tamalin / 192254	RGDID:	70554	Length:	394	Species:	Rattus norvegicus

Alignment Length:	333	Identity:	71/333 - (21%)
Similarity:	106/333 - (31%)	Gaps:	130/333 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 QRRLLVGGPERGSTYGFTVRG-GREHGTG------FFVSHVEHGGEAHLKGLRIGDQILRINGFR 128
            ||::|........|:||.::. |..|...      .||..|.....|.|.||..||.|..:||..
  Rat    97 QRKVLTLEKGDNQTFGFEIQTYGLHHREEQRVEMVTFVCRVHESSPAQLAGLTPGDTIASVNGLN 161

  Fly   129 LDDAVHKEFIQLVAGQDRVTLKVRGVGMLPVRDLPEERLSWSVVKLPSVSGTPSESS-------- 185
            ::...|:|.:.::                        :.|.:|::|.::.||....:
  Rat   162 VEGIRHREIVDII------------------------KASGNVLRLETLYGTSIRKAELEARLQY 202

  Fly   186 FKG---ERRGASRDISV----VLHVAPRTKLGLGICKGPEWKPGIFVQFTKDRSVAREAGLRPGD 243
            .|.   |:.|..|.:.|    ::|       || :.|    .|.|:......||....|||.||
  Rat   203 LKQTLYEKWGEYRSLMVQEQRLVH-------GL-VVK----DPSIYDTLESVRSCLYGAGLLPG- 254

  Fly   244 QILSVNSIDFSDVLFSEAVAVMKSSSKLDMVVRTAAGCDLFPGESSGYNSSASSVTGD------- 301
                  |:.|..:|.:                         ||.:.|.:..|...|.|
  Rat   255 ------SLPFGPLLAA-------------------------PGGARGGSRRAKGDTDDAVYHTCF 288

  Fly   302 ------------------------QSPCWADAKSKRLTAVREES----GAGGGGCGLSSAPGAGS 338
                                    ::|......:.|.|..|..|    |.||||.|  .||||
  Rat   289 FGGAEPQALPPPPPPARAPGPGSAETPASVLCPAPRATLSRSASVRCAGPGGGGGG--GAPGA-- 349

  Fly   339 PNWSQGVE 346
             .|::..|
  Rat   350 -LWTEARE 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5921	NP_727061.2	PDZ_signaling	82..152	CDD:238492	19/76 (25%)
CG5921	NP_727061.2	PDZ_signaling	197..276	CDD:238492	17/82 (21%)
Tamalin	NP_620249.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..51
		PDZ_signaling	99..184	CDD:238492	22/108 (20%)
		Interaction with PSCD3. /evidence=ECO:0000250	180..257		23/95 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	293..318		1/24 (4%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900