DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5921 and Lnx2

DIOPT Version :9

Sequence 1:NP_727061.2 Gene:CG5921 / 31538 FlyBaseID:FBgn0029835 Length:886 Species:Drosophila melanogaster
Sequence 2:NP_542985.4 Gene:Lnx2 / 140887 MGIID:2155959 Length:687 Species:Mus musculus


Alignment Length:294 Identity:63/294 - (21%)
Similarity:114/294 - (38%) Gaps:51/294 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    98 GFFVSHVEHGGEAHLKG-LRIGDQILRINGFRLDDAVHKEFIQLV-AGQDRVTLKVRGVGMLPVR 160
            |.|:..:..||.|...| |...|::|.|||..|.....:...|:: |..:||.|.:    ..|.:
Mouse   362 GVFILDLLEGGLAAQDGRLNSNDRVLAINGHDLKHGTPELAAQIIQASGERVNLTI----ARPGK 422

  Fly   161 DLPEERLSWSVVKLPSVSGTPSESSFKGERRGASRDIS-----VVLHVAPRTKLGLGICKGPEWK 220
            ..|......:.....|....|...|..|..:..:|.::     :.:...|...||:.:..|...|
Mouse   423 PQPSNGSREAGAHSSSNHAQPPSHSRPGSHKDLTRCVTCQEKHITVKKEPHESLGMTVAGGRGSK 487

  Fly   221 PG---IFVQFTKDRS-VAREAGLRPGDQILSVNSIDFSDVLFSEAVAVMKSSSKLDMVVRTAAGC 281
            .|   |||....... :||:..::.||.:|::|.||.:::..|||||::|:|:....|:..|...
Mouse   488 SGELPIFVTSVPPHGCLARDGRIKRGDVLLNINGIDLTNLSHSEAVAMLKASAASPAVILKALEV 552

  Fly   282 DLFPGESSGYNSSASSVTGDQSPCWADAKSKRLTAVREESGAGGGGCGLSSAPGAGSPNWSQGVE 346
            .:        ...|:..|.:|...:::                      :....:.||:|...:.
Mouse   553 QI--------AEEAAQATEEQPSAFSE----------------------NEYDASWSPSWVMWLG 587

  Fly   347 VHKQMNKTIIKLTENGTSINNTYIASTGGSSVSG 380
            :...::..      :...:..:|:.|.|.|.|.|
Mouse   588 LPSALHSC------HDIVLRRSYLGSWGFSIVGG 615

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5921NP_727061.2 PDZ_signaling 82..152 CDD:238492 18/55 (33%)
PDZ_signaling 197..276 CDD:238492 25/87 (29%)
Lnx2NP_542985.4 mRING-HC-C3HC3D_LNX2 46..90 CDD:319694
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 145..175
NPXY motif 207..210
PDZ 229..315 CDD:214570
PDZ_signaling 336..418 CDD:238492 18/59 (31%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 417..454 6/40 (15%)
PDZ_signaling 463..539 CDD:238492 23/75 (31%)
PDZ_signaling 596..680 CDD:238492 6/20 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3528
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.900

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