DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5921 and SYNJ2BP-COX16

DIOPT Version :9

Sequence 1:	NP_727061.2	Gene:	CG5921 / 31538	FlyBaseID:	FBgn0029835	Length:	886	Species:	Drosophila melanogaster
Sequence 2:	NP_001189476.1	Gene:	SYNJ2BP-COX16 / 100529257	HGNCID:	48350	Length:	191	Species:	Homo sapiens

Alignment Length:	166	Identity:	45/166 - (27%)
Similarity:	71/166 - (42%)	Gaps:	47/166 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 LVGGPERGSTYGFTVRGGRE-----HGTGFFVSHVEHGGEAHLKG-LRIGDQILRINGFRLDDAV 133
            |..||   |..||.:.||.:     :.:|.:||.::..|.|.|.| |:.||:||.:||..|.:.:
Human    16 LTRGP---SGLGFNIVGGTDQQYVSNDSGIYVSRIKENGAAALDGRLQEGDKILSVNGQDLKNLL 77

  Fly   134 HKEFIQLV--AGQDRVTLKV-------------RGVG----------MLPVRDLP------EERL 167
            |::.:.|.  ||. .|:|:|             ||.|          ::||..|.      |::|
Human    78 HQDAVDLFRNAGY-AVSLRVQHRLQVQNGPIGHRGEGDPSGIPIFMVLVPVFALTMMDPELEKKL 141

  Fly   168 SWSVVKLPSVSGTPSESSF------KGERRGASRDI 197
            ..:.:.|.|......:|.|      :|.|.....|:
Human   142 KENKISLESEYEKIKDSKFDDWKNIRGPRPWEDPDL 177

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5921	NP_727061.2	PDZ_signaling	82..152	CDD:238492	27/90 (30%)
CG5921	NP_727061.2	PDZ_signaling	197..276	CDD:238492	0/1 (0%)
SYNJ2BP-COX16	NP_001189476.1	PDZ_signaling	13..97	CDD:238492	29/84 (35%)
		DegQ	<16..77	CDD:223343	23/63 (37%)
		COX16	<133..173	CDD:290843	8/39 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900