DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MCTS1 and mcts1

DIOPT Version :9

Sequence 1:	NP_001245541.1	Gene:	MCTS1 / 31536	FlyBaseID:	FBgn0029833	Length:	182	Species:	Drosophila melanogaster
Sequence 2:	NP_957365.1	Gene:	mcts1 / 394046	ZFINID:	ZDB-GENE-040426-957	Length:	181	Species:	Danio rerio

Alignment Length:	183	Identity:	108/183 - (59%)
Similarity:	145/183 - (79%)	Gaps:	3/183 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFKKFEEKDSISSIQQLKSSVQKGIRAKLLEAYPKLESHIDLILPKKDSYRIAKCHDHIELL-LN 64
            |||||:||:::|:..|||:||.|||:.:||:.:|.::..::.|:||||..:|.:||:|||:| :|
Zfish     1 MFKKFDEKENVSNCIQLKTSVIKGIKNQLLDQFPNIDDWLNQIMPKKDPVKIVRCHEHIEILTVN 65

  Fly    65 GAGDQVFFRHRDGPWMPTLRLLHKFPYFVTMQQVDKGAIRFVLSGANVMCPGLTSPGACMTPADK 129
              |:.:|||.|:||:.||||||||:|:.:..||||||||:|||||||:||||||||||.:.||:.
Zfish    66 --GELLFFRQREGPFYPTLRLLHKYPFILPHQQVDKGAIKFVLSGANIMCPGLTSPGAKLYPAES 128

  Fly   130 DTVVAIMAEGKEHALAVGLLTLSTQEILAKNKGIGIETYHFLNDGLWKSKPVK 182
            |||||||||||:|||.||::.:|..:|...|.|||||..|:||||||..|..|
Zfish   129 DTVVAIMAEGKQHALCVGVMKMSADDIEKVNMGIGIENVHYLNDGLWHMKTYK 181

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MCTS1	NP_001245541.1	MCT1_N	4..81	CDD:211422	36/77 (47%)
		Tma20	18..177	CDD:224927	95/159 (60%)
		PUA	69..173	CDD:294405	68/103 (66%)
mcts1	NP_957365.1	MCT1_N	4..80	CDD:211422	36/77 (47%)
		Tma20	23..177	CDD:224927	93/155 (60%)
		PUA	64..172	CDD:294405	70/109 (64%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587187
Domainoid	1	1.000	109	1.000	Domainoid score	I6328
eggNOG	1	0.900	-	-		E1_COG2016
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5803
Inparanoid	1	1.050	227	1.000	Inparanoid score	I3461
OMA	1	1.010	-	-		QHG54154
OrthoDB	1	1.010	-	-		D1257440at2759
OrthoFinder	1	1.000	-	-		FOG0003649
OrthoInspector	1	1.000	-	-		oto41630
orthoMCL	1	0.900	-	-		OOG6_101211
Panther	1	1.100	-	-	LDO	PTHR22798
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2520
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.770