DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MCTS1 and SPBC31F10.12

DIOPT Version :9

Sequence 1:	NP_001245541.1	Gene:	MCTS1 / 31536	FlyBaseID:	FBgn0029833	Length:	182	Species:	Drosophila melanogaster
Sequence 2:	NP_596574.2	Gene:	SPBC31F10.12 / 2540396	PomBaseID:	SPBC31F10.12	Length:	181	Species:	Schizosaccharomyces pombe

Alignment Length:	181	Identity:	88/181 - (48%)
Similarity:	120/181 - (66%)	Gaps:	6/181 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFKKFEEKDSISSIQQLKSSVQKGIRAKLLEAYPKLESHIDLILPKKDSYRIAKCHDHIEL-LLN 64
            |||:|..::.|.....:|||:|:||:|||::|||.|:..||.::|||......||.|.:.| .||
pombe     1 MFKRFNSREDIKGTTPIKSSIQRGIKAKLVQAYPNLKQVIDELIPKKSQLTQIKCEDRLFLYTLN 65

  Fly    65 GAGDQVFFRHRDGPWMPTLRLLHKFPYFVTMQQVDKGAIRFVLSGANVMCPGLTSPGACMTPAD- 128
              |:.:.|:|.|||.:|:|||:||.|...|..:||:|||:|:|||||:|.|||.|.|..: |.|
pombe    66 --GEIILFQHFDGPIIPSLRLVHKCPDAFTQVRVDRGAIKFLLSGANIMIPGLVSKGGNL-PDDI 127

  Fly   129 -KDTVVAIMAEGKEHALAVGLLTLSTQEILAKNKGIGIETYHFLNDGLWKS 178
             ||..|.:.|||||...|:||..:|.:|:...|||||||..|:|.|.|||:
pombe   128 EKDQYVIVTAEGKEAPAAIGLTKMSAKEMKETNKGIGIENVHYLGDNLWKT 178

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MCTS1	NP_001245541.1	MCT1_N	4..81	CDD:211422	32/77 (42%)
		Tma20	18..177	CDD:224927	81/161 (50%)
		PUA	69..173	CDD:294405	54/105 (51%)
SPBC31F10.12	NP_596574.2	MCT1_N	4..80	CDD:211422	32/77 (42%)
		Tma20	13..181	CDD:224927	83/169 (49%)
		PUA	62..173	CDD:294405	57/113 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	78	1.000	Domainoid score	I2392
eggNOG	1	0.900	-	-		E1_COG2016
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5803
Inparanoid	1	1.050	166	1.000	Inparanoid score	I1213
OMA	1	1.010	-	-		QHG54154
OrthoFinder	1	1.000	-	-		FOG0003649
OrthoInspector	1	1.000	-	-		oto101644
orthoMCL	1	0.900	-	-		OOG6_101211
Panther	1	1.100	-	-	LDO	PTHR22798
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1530
SonicParanoid	1	1.000	-	-		X2520
TreeFam	1	0.960	-	-
	14	13.860