DRSC/TRiP Functional Genomics Resources

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Protein Alignment MCTS1 and Eif2d

DIOPT Version :10

Sequence 1:NP_572288.1 Gene:MCTS1 / 31536 FlyBaseID:FBgn0029833 Length:182 Species:Drosophila melanogaster
Sequence 2:XP_006529228.1 Gene:Eif2d / 16865 MGIID:109342 Length:587 Species:Mus musculus


Alignment Length:189 Identity:50/189 - (26%)
Similarity:89/189 - (47%) Gaps:21/189 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MF-KKFEEKDSISSIQQLKSSVQKGIRAKLLEAYPKL-ESHIDLILPKKDSYRIAKCH----DHI 59
            || |.|..|.:.:    :|.|.::.:||.:..|:|.| ...|..::|.|:...:.|.:    |.:
Mouse     1 MFAKAFRVKSNTA----IKGSDRRKLRADVTAAFPALGTDQISELIPGKEELNVVKLYVHKGDSV 61

  Fly    60 ELLLNGAGDQVFFRHRDGPWMPTLRLLHKF----PYFVTMQQVDKGAIRFVLSGANVMCPGLTSP 120
            .:..:| |:.:.|......: ||:..|..:    |.|:|...|    :..::.||::|.||:..|
Mouse    62 TVYTSG-GNPILFELEKNLY-PTVYTLWAYPDILPTFITWPLV----LEKLVGGADLMLPGVVVP 120

  Fly   121 GACMTPADKDTVVAIMAEGKEHALAVGLLTLSTQEILAKN-KGIGIETYHFLNDGLWKS 178
            ...:....:..:.||...|....:|:|:..:||.::||.. ||.|:...|...|.||:|
Mouse   121 PTGLPQVQQGDLCAIALVGNRAPVAIGVAAMSTAQMLASGLKGKGVSVLHTYQDHLWRS 179

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MCTS1NP_572288.1 MCT1_N 4..81 CDD:211422 17/81 (21%)
PUA_MCTS-1-like 81..176 CDD:409297 27/99 (27%)
Eif2dXP_006529228.1 Pre-PUA 2..90 CDD:436077 22/93 (24%)
PUA_eIF2d-like 92..173 CDD:409298 23/84 (27%)
eIF2D_C 477..550 CDD:211321
Blue background indicates that the domain is not in the aligned region.

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