DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Atf7 and kay

DIOPT Version :9

Sequence 1:	NP_001101585.1	Gene:	Atf7 / 315333	RGDID:	1304940	Length:	485	Species:	Rattus norvegicus
Sequence 2:	NP_001027577.2	Gene:	kay / 3772082	FlyBaseID:	FBgn0001297	Length:	755	Species:	Drosophila melanogaster

Alignment Length:	397	Identity:	89/397 - (22%)
Similarity:	146/397 - (36%)	Gaps:	108/397 - (27%)

- Green bases have known domain annotations that are detailed below.

  Rat   170 TLPSPTSVITQAPPSNRQIGSPTGSLPLVMHLANGQTMPMLPGPPVQMPSVISLARPVSMVPNIP 234
            ||.:|    |..|.:.|.|....|.|     |::.||..:.......:|.|:..|..| :...||
  Fly   246 TLTTP----TLTPTTTRNIEDTLGHL-----LSDTQTDRVAGCAGFAVPKVLPNAIDV-LGMGIP 300

  Rat   235 -GIPGPPVNNS-------GSISPSGHPMPSEAKMRLKATLTHQVS----------------SING 275
             |:...|:..:       ||.|...:...::.:|..:...|...|                |:||
  Fly   301 TGVSSLPLQQTFDLSLGQGSESEDSNASYNDTQMNEEQDTTDTSSAHTDSTSYQAGHIMAGSVNG 365

  Rat   276 G-----CGMVVGTASTMVTARPEQNQILIQHPDAPSPAQPQVSPAQPTPSTGGRR-RRTVDEDPD 334
            |     ..::...:|:..:|..           ..|.|....:||:   ..|||| .|:.:..|:
  Fly   366 GGVNNFSNVLAAVSSSRGSASV-----------GSSNANTSNTPAR---RGGGRRPNRSTNMTPE 416

  Rat   335 ERRQRFL--ERNRAAASRCRQKRKLWVSSLEKKAEELTSQNIQLSNEVTLLRNEVAQLKQLLLAH 397
            |.::|.:  |||:.||:|||::|....:.|.::.|:|..:...:..|:.:|.|...||:.||..|
  Fly   417 EEQKRAVRRERNKQAAARCRKRRVDQTNELTEEVEQLEKRGESMRKEIEVLTNSKNQLEYLLATH 481

  Rat   398 K--------------DC-----PVTALQKKTQGYLESPKESSEPTGSPAPVIQHSSATAPSNG-- 441
            :              .|     |...|...:.|...|...:.....|....|....||..|.|
  Fly   482 RATCQKIRSDMLSVVTCNGLIAPAGLLSAGSSGSGASSHHNHNSNDSSNGTITGMDATLNSTGRS 546

  Rat   442 ---LSVRSAAEAVATSVLTQMASQRTE-------------------LSMPIQS---HV----IMT 477
               |.::.||.  ..|:|..:..:..:                   :::|..|   ||    |:|
  Fly   547 NSPLDLKPAAN--IDSLLMHIKDEPLDGAIDSGSSLDQDGPPPSKRITLPPMSTMPHVHLSTILT 609

  Rat   478 PQSQSAG 484
            |...|:|
  Fly   610 PTGASSG 616

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atf7	NP_001101585.1	C2H2 Zn finger	9..31	CDD:275368
		GCN4_cent	47..84	CDD:213399
		bZIP_ATF2	336..396	CDD:269835	20/61 (33%)
		coiled coil	336..396	CDD:269835	20/61 (33%)
kay	NP_001027577.2	bZIP_Fos	420..481	CDD:269869	20/60 (33%)
kay	NP_001027577.2	coiled coil	421..480	CDD:269869	20/58 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1414
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810