Protein Alignment CG4766 and MAB21L4

DIOPT Version :10

• Sequence 1: NP_572287.1
• Gene: CG4766 / 31533
• FlyBaseID: FBgn0027546
• Length: 368
• Species: Drosophila melanogaster
• Sequence 2: NP_001078906.3
• Gene: MAB21L4 / 79919
• HGNCID: 26216
• Length: 447
• Species: Homo sapiens
• Alignment Length: 372
• Identity: 75/372 - (20%)
• Similarity: 139/372 - (37%)
• Gaps: 46/372 - (12%)

  Fly     3 VPPDMMAAQTRMVYQMNRFCTERVQARMYKTATAIREICKIVQDILKEVELQEPRFISSLVECNG 67
            :|...||.|..:.:..    .:.:::|....|...:....::..:|:.|...:||||   |:.:.
Human     6 LPTSAMAVQVPLWHHY----LQAIRSREAPRAQDFQRAENVLLTVLERVHALDPRFI---VDYSR 63

  Fly    68 RFEGVEVI-----SPNEFEIVLYLNQMGVFNFVDDGTLP--GCAVLKLSDGRK-RSMSLWV--EF 122
            ..|..:..     .|.:.|:.|:::...:.....:.|.|  |..:..|...|: ..:..|.  :.
Human    64 GLEAFQFALRSSEDPMDMEVPLWVDAEALLIEEPEATQPEDGLELCHLGVPREGAGLERWTTEDT 128

  Fly   123 ITAS--------GYLSSRKIRARFQTLVAQACDKSVYRDMVKMVGDTSEVKLRIRERFVVQITPA 179
            .|||        |::...|:....:.|:..|.....:..:: ..|..:...||..     |:..:
Human   129 FTASSEGDAKCRGHIVPSKVLCVLKDLLVAAIVHCKHHSLI-APGSLNAASLREE-----QLHLS 187

  Fly   180 FKCSGIWPRSAAH-WPVPHLPWPHPNIVAEVKTEGFDLLSKESVIMQNKNNNAASMEGDAWVLSF 243
            ...|..|...:.| .||.......|.:....:..||...|...::.|..:...||.:  .|..|.
Human   188 LLVSSGWRTISFHVVPVVRRKLGAPALEGVQQMPGFPEGSLRRILSQGVDLVPASAQ--LWRTST 250

  Fly   244 FEAENRLL-----QGGCRRRCLSMLKTLRDRHLDLPG--NPISAYHLKNLLLYECEKHPRDFEWD 301
            .....|||     ..|.|...||:|..:........|  :.::..|||.:||:.........:|.
Human   251 DYLLTRLLGELGSLQGHRLDSLSILDRVNHESWRDSGQTDGLTFGHLKMVLLWASVLFLAPEDWA 315

  Fly   302 EGCIADRINGIFLQLISCLQYRRCPHYFLPALDMFKGKSPSALEQAA 348
            |  :...:..:.:.|:.||..|:.||:..|..::.:|   |.|:..|
Human   316 E--LQGAVYRLLVVLLCCLATRKLPHFLHPQRNLLQG---SGLDLGA 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4766	NP_572287.1	Mab-21	68..253	CDD:460873	38/208 (18%)
		Mab-21_C	255..353	CDD:466416	23/96 (24%)
MAB21L4	NP_001078906.3	Mab-21_C	<296..350	CDD:466416	14/55 (25%)